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56485

N-Hydroxysulfosuccinimid Natriumsalz

≥98% (HPLC), for peptide synthesis

Synonym(e):

Hydroxy-2,5-dioxopyrrolidin-3-sulfonsäure Natriumsalz, Sulfo-NHS

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250 MG

€ 109,00

1 G

€ 281,00

5 G

€ 1.140,00

€ 109,00


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Über diesen Artikel

Empirische Formel (Hill-System):
C4H4NNaO6S
CAS-Nummer:
Molekulargewicht:
217.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Beilstein/REAXYS Number:
6359129

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Produktname

N-Hydroxysulfosuccinimid Natriumsalz, ≥98% (HPLC)

InChI

1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1

SMILES string

[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O

InChI key

RPENMORRBUTCPR-UHFFFAOYSA-M

assay

≥98% (HPLC)

form

powder

composition

carbon, 20.90-22.68 (anhydrous)
nitrogen, 6.10-6.61 (anhydrous)

reaction suitability

reaction type: Addition Reactions

impurities

≤4% water

application(s)

peptide synthesis

functional group

imide
sulfonic acid

Quality Level

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Dieser Artikel
56480130672SML2148
form

powder

form

solid

form

solid

form

powder

functional group

imide, sulfonic acid

functional group

imide

functional group

imide

functional group

-

assay

≥98% (HPLC)

assay

≥97.0% (T)

assay

98%

assay

≥95% (HPLC)

impurities

≤4% water

impurities

-

impurities

-

impurities

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

composition

carbon, 21.57-22.68 (anhydrous)

composition

-

composition

-

composition

-

Application

N-Hydroxysulfosuccinimid Natriumsalz ist ein wasserlösliches sulfoniertes Analogon von N-Hydroxysuccinimid. Es kann in Gegenwart von Carbodiimiden wie 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimid (EDC) eine Kopplungsreaktion mit Carboxylsäuren eingehen, wobei hydrophile N-Hydroxysulfosuccinimid-Aktivester gebildet werden. Diese Ester sind bei Protein-Vernetzungsversuchen nützlich.[1][2]

Other Notes

Sulfo-NHS wird zur Herstellung hydrophiler Aktivester, wie z.B. für Vernetzungsmittel, verwendet.[3][4]

Packaging

Bodenlose Glasflasche. Der Inhalt befindet sich innerhalb des eingeschmolzenen Einsatzes.

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Karen S Cheung Tung Shing et al.
Scientific reports, 8(1), 12457-12457 (2018-08-22)
A direct interaction between the erythropoietin (EPOR) and the beta-common (βc) receptors to form an Innate Repair Receptor (IRR) is controversial. On one hand, studies have shown a functional link between EPOR and βc receptor in tissue protection while others
R Maydelid Trujillo-Nolasco et al.
Materials science & engineering. C, Materials for biological applications, 103, 109766-109766 (2019-07-28)
Radiosynovectomy is a technique used to decrease inflammation of the synovial tissue by intraarticular injection of a β-emitting radionuclide, such as 177Lu, which is suitable for radiotherapy due to its decay characteristics. Drug-encapsulating nanoparticles based on poly lactic‑co‑glycolic acid (PLGA)
P S Anjaneyulu et al.
International journal of peptide and protein research, 30(1), 117-124 (1987-07-01)
N-Hydroxysulfosuccinimide esters are reactive functional groups employed in a variety of protein modification reagents, especially cross-linking reagents. For these compounds, hydrolysis is the most important reaction competing for reaction of the esters with nucleophilic groups in proteins. We have employed
Xiao-Yan Xu et al.
Journal of materials chemistry. B, 7(32), 4963-4972 (2019-08-15)
The construction of antibacterial and antitumor coatings could offer effective routes to improve the therapeutic effects of non-vascular stents for unresectable obstructions caused by malignant tumours. Herein, polyelectrolyte multilayers have been explored as bactericidal coatings with controlled antitumor drug release.
N-hydroxysulfosuccinimide active esters: bis (N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers.
Staros JV
Biochemistry, 21(17), 3950-3955 (1982)

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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What are the storage conditions for product 56485? There are no recommended conditions. Is it Room temp?

    1 answer
    1. As mentioned in the Material Safery Data Sheet, section 7, it is recommended to store under inert gas such as argon or nitrogen. Please see the link below to review the SDS:
      https://www.sigmaaldrich.com/sds/aldrich/56485

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