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RAB0441

Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit

for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates

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Größe/SKUVerfügbarkeitPreis
1 kit
Versand in der Regel in 1 Woche. (Bei Bestellungen außerhalb der USA und Europas rechnen Sie bitte zusätzlich 1-2 Wochen für die Lieferung ein)
€ 735,00

Über diesen Artikel

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... STAT1(6772)
mouse ... STAT1(20846)
Species reactivity:
mouse, human
Storage temp.:
−20°C
Shipped in:
wet ice

€ 735,00

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Versand in der Regel in 1 Woche. (Bei Bestellungen außerhalb der USA und Europas rechnen Sie bitte zusätzlich 1-2 Wochen für die Lieferung ein)
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Unterstützung erhalten

species reactivity

mouse, human

technique(s)

ELISA: suitable, capture ELISA: suitable

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

General description

The Phospho-Stat1 (pSer727) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

Immunogen

Stat1 (pTyr727) synthetic phosphopeptide, Recombinant Human STAT1

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Signal transducer and activator of transcription 1 (STAT1) undergoes phosphorylation on serine-727. This Phospho-Stat1 regulates pro- and anti-apoptotic genes following several stress-induced responses. STAT-1 interacts with p53 and promotes p53-mediated transcriptional gene activity and apoptosis. STAT-1 is an essential factor of stress-induced and DNA damage-induced checkpoint pathways and thus, acts as a tumour suppressor. STAT-1 functions as a pro-apoptotic factor in cardiac myocytes, brain or liver exposed to ischaemia–reperfusion injury. Thus, inhibition of STAT-1-activated pathway by epigallocatechin-3-gallate (EGCG), can be considered as a potential therapeutic method against ischaemic tissue injury. Repression of STAT-1 expression by human papillomavirus (HPV) oncoproteins E6 and E7 at transcription level is essential for genome amplification and maintenance of episomes, which is suggested to have a crucial role in viral pathogenesis.

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Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates

Sigma-Aldrich

RAB0441

Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit

Phospho-Stat1 (pTyr701) ELISA Kit for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates

Sigma-Aldrich

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Phospho-Stat1 (pTyr701) ELISA Kit

Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines 192 assays

Sigma-Aldrich

RAB0454

Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines

Phospho-Akt (pSer473) / pan-Akt ELISA Kit for detection of human, mouse or rat phospho-akt (pSer473) and pan-akt in cell and tissue lysates

Sigma-Aldrich

RAB0012

Phospho-Akt (pSer473) / pan-Akt ELISA Kit

description

for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates

description

for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates

description

192 assays

description

for detection of human, mouse or rat phospho-akt (pSer473) and pan-akt in cell and tissue lysates

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

Gene Information

human ... STAT6(6778)
mouse ... STAT6(20852)
rat ... STAT6(362896)

Gene Information

human ... AKT1(207)

species reactivity

mouse, human

species reactivity

human, mouse

species reactivity

rat, human, mouse

species reactivity

human, mouse, rat

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

signalword

Warning

flash_point_f

Not applicable

flash_point_c

Not applicable

pictograms

Corrosion
GHS05

hcodes

H290

Hazard Classifications

Met. Corr. 1

Lagerklasse

12 - Non Combustible Liquids

Hier finden Sie alle aktuellen Versionen:

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