RAB0721

Human PDCD1 / Programmed Cell Death Protein 1 ELISA Kit

• NACRES: NA.84
• UNSPSC Code: 41116158
• Gene information: human ... PDCD1(5133)
• Input: sample type cell culture supernatant(s); sample type plasma; sample type serum
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Eigenschaften

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type cell culture supernatant(s); sample type plasma; sample type serum
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 20 pg/mL; standard curve range: 24.58-6000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... PDCD1(5133)

Beschreibung

General description

The antibody pair provided in this kit recognizes human Programmed Cell Death Protein 1.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Programmed cell death protein 1 (PDCD1) plays an important role in the immune regulation by acting as a negative co-stimulatory factor. It suppresses the functions and multiplication of T cells, thereby reducing the release of IL-2 (interleukin-2), IL-10 and IFN-γ (interferon γ). In the presence of tumor microenvironment, PDCD1 along with its ligand modulates T effector functioning, thereby protecting cancer cells from immune-associated rejection. Mutation in this gene is associated with symptoms and progression of multiple sclerosis and susceptibility to systemic lupus erythematosus.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• Gefahrencodes: H334
• Sicherheitshinweise: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Lagerklasse: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable