RAB0797

Mouse IgA ELISA Kit

• Synonym(e): IgA, Immunoglobulin A
• NACRES: NA.32
• UNSPSC Code: 41116158
• Species reactivity: mouse
• Storage temp.: −20°C
• Shipped in: wet ice

Eigenschaften

• species reactivity: mouse
• technique(s): ELISA: suitable
• assay range: inter-assay cv: <10%; intra-assay cv: <12%
• shipped in: wet ice
• storage temp.: −20°C

Beschreibung

General description

The antibody pair provided in this kit recognizes Mouse IgA.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Immunoglobulin A (IgA) is majorly found in the mucosal secretions. IgA exists as two subclasses, IgA1 and IgA2. IgA is a dimer in animals, but a monomer in humans. IgA interacts with the Fc fragment of IgA receptor (FCAR) to elicit immune response against inhaled pathogens. Secretory IgA (S-IgA) produced by B1 lymphocytes triggers phagocytosis and leucocyte respiratory burst. S-IgA exists as a polymer and is crucial for primary defense. The high levels of IgA in human milk and colostrum may provide immune protection to infants. Deficiency of IgA leads to increased susceptibility to infections. High levels of IgA in kidney is present in IgA nephropathy and IgA myeloma. Autoantibodies of IgA is present in celiac disease.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Sicherheitshinweise

• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Lagerklasse: 10 - Combustible liquids
• Piktogramme: GHS08
• Signalwort: Danger
• Gefahrencodes: H334
• Sicherheitshinweise: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1