SAB3500576

Anti-MFSD2A antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Mfsd2A Antibody, Mfsd2A Antibody - Anti-MFSD2A antibody produced in rabbit, Anti-Major facilitator superfamily domain-containing protein 2A, Anti-mfsd2aa
• NACRES: NA.41
• UNSPSC Code: 12352203

Eigenschaften

• Produktname: Anti-MFSD2A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse, rat, human
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI accession no.: NP_001007452
• UniProt accession no.: Q5U3U7
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: zebrafish ... mfsd2aa(492810)

Beschreibung

Biochem/physiol Actions

Major facilitator superfamily domain containing 2a (Mfsd2a) acts as a transporter for the essential omega-3 fatty acid docosahexaenoic acid. It is essential at the blood-brain barrier for postnatal brain growth. A leaky blood-brain barrier from embryonic stages through to adulthood is observed if there is a genetic variation in this gene. Mutation in MFSD2A gene results in microcephaly and ventriculomegaly.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Major facilitator superfamily domain containing 2a (Mfsd2a)is a sodium-dependent lysophosphatidylcholine (LPC) transporter. The endothelium of the micro vessels in blood brain barrier express high levels of Mfsd2a.

Immunogen

MFSD2A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MFSD2A.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500576.

Physical form

Supplied in PBS with 0.02% sodium azide.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable