SML4027

ZH8659 hydrochloride

≥98% (HPLC)

• Synonym(e): 2-[4-(Furan-2-yl)phenyl]ethan-1-amine hydrochloride, 4-(2-Furanyl)benzene-ethanamine hydrochloride
• Empirische Formel (Hill-System): C₁₂H₁₃NO ·HCl
• Molekulargewicht: 223.70
• NACRES: NA.21
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: NCCC1=CC=C(C2=CC=CO2)C=C1.Cl
• InChI: 1S/C12H13NO.ClH/c13-8-7-10-3-5-11(6-4-10)12-2-1-9-14-12;/h1-6,9H,7-8,13H2;1H
• InChI key: PIDHDDFXZYDGMH-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Orally available, potent and selective agonist of Trace amine-associated receptor 1 (TAAR1); potent Gq-selective agonist of mTAAR1/hTAAR1.

ZH8659 is an orally available, potent and selective agonist of Trace amine-associated receptor 1 (TAAR1). ZH8659 is a potent Gq-selective agonist of mTAAR1/hTAAR1 (EC50 = 2.6 nM (Gq)). ZH8659 alleviates MK-801-induced schizophrenia-like phenotypes without inducing catalepsy in mice.

Disclaimer

Hygroscopic

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable