SML4026

ZH8651 hydrochloride

≥98% (HPLC)

• Synonym(e): 2-(4-Bromophenyl)ethan-1-amine hydrochloride, 4-Bromobenzene-ethanamine hydrochloride, 4-Bromophenethylamine hydrochloride, p-Bromophenethylamine hydrochloride
• Empirische Formel (Hill-System): C₈H₁₀BrN ·HCl
• CAS-Nummer: 39260-89-4
• Molekulargewicht: 236.54
• UNSPSC Code: 12352200
• MDL number: MFCD09037950
• NACRES: NA.21
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: BrC1=CC=C(C=C1)CCN.Cl
• InChI: 1S/C8H10BrN.ClH/c9-8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
• InChI key: ZHAWIPAHUYMLDV-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Orally available, potent, and selective agonist of Trace amine-associated receptor 1 (TAAR1); dual activator of Gs and Gq in mTAAR1/hTAAR1.



ZH8651 is an orally available, potent, and selective agonist of Trace amine-associated receptor 1 (TAAR1). ZH8651 is dual activator of Gs and Gq in mTAAR1/hTAAR1 (EC50 = 9,85 nM (Gs), 66.5 nM Gq). ZH8651 alleviates MK-801-induced schizophrenia-like phenotypes without inducing catalepsy in mice.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319
• Sicherheitshinweise: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable