V4765

Valnoctamide

≥98% (NMR)

• Synonym(e): 2-ethyl-3-methyl-pentanamide, Axiquel, Nirvanil
• Empirische Formel (Hill-System): C₈H₁₇NO
• CAS-Nummer: 4171-13-5
• Molekulargewicht: 143.23
• NACRES: NA.77
• PubChem Substance ID: 329829054
• UNSPSC Code: 12352200
• MDL number: MFCD00868184
• Assay: ≥98% (NMR)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (NMR)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: room temp
• SMILES string: CCC(C)C(CC)C(N)=O
• InChI: 1S/C8H17NO/c1-4-6(3)7(5-2)8(9)10/h6-7H,4-5H2,1-3H3,(H2,9,10)
• InChI key: QRCJOCOSPZMDJY-UHFFFAOYSA-N

Beschreibung

Application

Valnoctamide has been used:

• as a mood stabilizer to study its anti-cytomegalovirus (anti-CMV) effects in newborn mice brain
• as a hypnotic sedative to study its cytotoxic effects on oligodendrocyte precursor cells (OPCs) and human oligodendroglioma cell line (HOG)
• as a mood stabilizer to study its effects on inhibition of human cytomegalovirus

Biochem/physiol Actions

Valproic acid (VPA) and derivatives such as valpromide and valnoctamide are anti-convulsant, mood stabilizing drugs, believed to function as indirect GABA agonists by inhibiting the transamination of GABA.

Valnoctamide exhibits anti-cytomegalovirus (anti-CMV) properties. It has therapeutic effects against status epilepticus (SE) and neuropathic pain. Valnoctamide also shows therapeutic effects against bipolar disorders.

Features and Benefits

This compound is featured on the Glutamate/GABA Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable