1237382

Epirubicin -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 4′-Epidoxorubicin -hydrochlorid, Epidoxorubicin -hydrochlorid
• Empirische Formel (Hill-System): C₂₇H₂₉NO₁₁ · HCl
• CAS-Nummer: 56390-09-1
• Molekulargewicht: 579.98
• NACRES: NA.24
• PubChem Substance ID: 329749729
• UNSPSC Code: 41116107
• MDL number: MFCD00941448

Eigenschaften

• Produktname: Epirubicin -hydrochlorid, United States Pharmacopeia (USP) Reference Standard
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1
• SMILES string: Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
• InChI key: MWWSFMDVAYGXBV-FGBSZODSSA-N
• grade: pharmaceutical primary standard
• API family: epirubicin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C

Beschreibung

Biochem/physiol Actions

Zellpermeables Anthracyclin. Ein Antitumor-Antibiotikum und Antineoplastikum. Ein Stereoisomer von Doxorubicin, das reduzierte Kardiotoxizität aufweist. Die Antitumor Aktivitäten sind ausgerichtet auf Topoisomerase II.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Epirubicin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Doxorubicin Hydrochloride
• Doxorubicin Hydrochloride for Injection
• Doxorubicin Hydrochloride Injection
• Epirubicin Hydrochloride
• Epirubicin Hydrochloride Injection

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H340,H350,H360
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable