567021

Simvastatin Sodium Salt

HMG-CoA reductase inhibitor, (Beige solid)

• Synonym(e): L-Type Calcium Channel Blocker VI, Simvastatin, Sodium Salt - Calbiochem
• Lineare Formel: C25H39O6.Na
• UNSPSC-Code: 51111800
• NACRES: NA.32

Eigenschaften

• Produktname: Simvastatin, Sodium Salt - Calbiochem,
• Form: (Beige solid)
• Qualitätsniveau: 100
• Lagerbedingungen: OK to freeze
• Löslichkeit: soluble (DMSO (100 mg/ml), Ethanol (25 mg/ml), or H2O (5 mg/ml))
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+-signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. Note: This product is supplied in an active form; no treatment with NaOH in ethanol is required for its activation.