(−)-Bilobalide

Name: (−)-Bilobalide
Brand: SIAL
Price: 316 CHF

analytical standard

Sinonimo/i:

Bilobalide

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10 MG

CHF 316.00

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₅H₁₈O₈

Numero CAS:

33570-04-6

Peso molecolare:

326.30

Numero MDL:

MFCD00132880

Codice UNSPSC:

85151701

ID PubChem:

329768523

NACRES:

NA.24

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Grado

analytical standard

Livello qualitativo

100

Saggio

≥96.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)C[C@]23C(=O)O[C@@H]4OC(=O)[C@H](O)C134

InChI

1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13+,14+,15?/m0/s1
MOLPUWBMSBJXER-DXPZGIEZSA-N

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Questo articolo	94970	18309	B9031
Supelco 79593 (−)-Bilobalide	Supelco 94970 Ginkgolide B	Supelco 18309 Ginkgolide C	Sigma-Aldrich B9031 (−)-Bilobalide from Ginkgo biloba leaves
application(s) food and beverages	application(s) food and beverages	application(s) food and beverages	application(s) -
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
grade analytical standard	grade analytical standard	grade analytical standard	grade -
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C
assay ≥96.0% (HPLC)	assay -	assay ≥96.0% (HPLC)	assay ≥93% (HPLC)

Descrizione generale

(−)-Bilobalide is a Ginkgo terpenoid, available as the main pharmacological component in Ginkgo biloba extract.[1] It exhibits neuroprotectant activity.[1]

Applicazioni

(−)-Bilobalide may be used as an analytical rstandard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.[2]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

This compound is commonly found in plants of the genus: ginkgo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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LC-ESI-MS determination of bilobalide and ginkgolides in canine plasma

Tang J, et al.

Chromatographia, 63(1-2), 53-58 (2006)

Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats

Xie J, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 87-94 (2008)

Ginkgo biloba extract (EGb761) inhibits mitochondria-dependent caspase pathway and prevents apoptosis in hypoxia-reoxygenated cardiomyocytes.

Jiangang Shen et al.

Chinese medicine, 6, 8-8 (2011-02-25)

EGb761 is a standard extract from the leaves of Ginkgo biloba (Yinxing) containing ginkgo-flavone glycosides and terpenoid. The flavonoid components of EGb761 scavenge free radicals and protect myocardia from ischemia-reperfusion injury. The present study aims to determine the effects of

The facilitative effects of bilobalide, a unique constituent of Ginkgo biloba, on synaptic transmission and plasticity in hippocampal subfields.

Etsuko Suzuki et al.

The journal of physiological sciences : JPS, 61(5), 421-427 (2011-06-29)

Bilobalide, a unique constituent of Ginkgo biloba, has been reported to potentiate population spikes in hippocampal CA1 pyramidal cells and to protect the brain against cell death. In this study, the effects of bilobalide on synaptic transmission and its plasticity

Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans.

Karin Woelkart et al.

Phytotherapy research : PTR, 24(3), 445-450 (2009-12-31)

A sensitive LC-ESI-MS method with a solid-phase extraction was established for the determination of bilobalide, ginkgolide A and ginkgolide B in human plasma; bioavailability and pharmacokinetics of three different Ginkgo biloba L. preparations have been investigated. The preparations used in

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(−)-Bilobalide