The product MAK106 uses linear regression fitting. The standard curve is prepared based on the donor particle concentration indicated on the label, which is batch-specific. The standard curve in table 2 is representative and for example purposes only. It's important to note that the concentrations may vary. The pmole values are calculated through dimension analysis using the amount of donor particle solution used and any subsequent dilution. For example, the most concentrated standard can be calculated by considering the volume of the donor particle. In this case, the most concentrated standard has 130 pmoles. Each subsequent dilution is two times less concentrated, resulting in concentrations of 65, 32.5, 16.25, and 8.1 pmoles.
MAK106
CETP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Sinonimo/i:
Cholesteryl ester transfer protein activity assay kit
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1 KIT
CHF 699.00
Informazioni su questo articolo
Codice UNSPSC:
12161503
NACRES:
NA.84
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Permettici di aiutartiimpiego
sufficient for 100 fluorometric tests
applicazioni
pharmaceutical
Metodo di rivelazione
fluorometric
Malattie correlate
cardiovascular diseases
Temperatura di conservazione
2-8°C
Informazioni sul gene
human ... CETP(1071)
1 of 4
Questo articolo | MAK305 | MAK108 | MAK110 |
|---|---|---|---|
| Gene Information human ... CETP(1071) | Gene Information - | Gene Information human ... PLTP(5360) | Gene Information human ... MTTP(4547) |
| usage sufficient for 100 fluorometric tests | usage sufficient for 100 fluorometric tests | usage sufficient for 100 fluorometric tests | usage sufficient for 100 fluorometric tests |
| detection method fluorometric | detection method fluorometric | detection method fluorometric | detection method fluorometric |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| application(s) pharmaceutical | application(s) pharmaceutical | application(s) pharmaceutical | application(s) pharmaceutical |
| relevant disease(s) cardiovascular diseases | relevant disease(s) cardiovascular diseases | relevant disease(s) cardiovascular diseases | relevant disease(s) cardiovascular diseases |
Descrizione generale
Cholesteryl ester transfer protein (CETP) is present in normal human plasma. The protein transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway. The method is useful for measuring CETP activity in plasma or serum in all species that express CETP.
Applicazioni
Cholesteryl ester transfer protein (CETP) activity Assay Kit has been used for measurement of CETP activity in the plasma samples.[1]
Suitable for the detection of cholesteryl ester transfer protein (CETP) in plasma / serum (fresh or frozen), recombinant or purified CETP.
Azioni biochim/fisiol
The CETP Activity Assay Kit uses a proprietary substrate that enables the detection of CETP-mediated transfer of neutral lipid from the substrate to a physiological acceptor. The transfer activity results in an increase in fluorescence intensity (λEx=535 nm/λEm=587 nm). In a total volume of 200 μL, the assay is linear from 0.2 to 0.8 μL of normal human plasma. Assay results not affected by endogenous plasma HDL, LDL or VLDL concentrations.
Caratteristiche e vantaggi
Compatible with high-throughput handling systems.
Risultati analitici
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
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Zhaosha Li et al.
Biochemical pharmacology, 84(6), 821-829 (2012-07-04)
The anti-dyslipidemic drug niacin has recently been shown to reduce the hepatic expression and plasma levels of CETP. Since liver macrophages contribute to hepatic CETP expression, we investigated the role of macrophages in the CETP-lowering effect of niacin in mice.
Lisa Sawrey-Kubicek et al.
The American journal of clinical nutrition, 110(3), 617-627 (2019-06-07)
Postmenopausal women are at higher risk for cardiovascular disease (CVD) than their younger counterparts. HDL cholesterol is a biomarker for CVD risk, but the function of HDL may be more important than HDL cholesterol in deciphering disease risk. Although diet
Catherine J McNeal et al.
Cardiovascular research, 98(1), 83-93 (2013-01-29)
We discovered that some adults with coronary heart disease (CHD) have a high density lipoprotein (HDL) subclass which induces human aortic smooth muscle cell (ASMC) apoptosis in vitro. The purpose of this investigation was to determine what properties differentiate apoptotic
Thor Ueland et al.
The Journal of clinical endocrinology and metabolism, 105(3) (2019-10-31)
Cholesteryl ester transfer protein (CETP) regulates high-density lipoprotein (HDL) cholesterol levels and interaction between glucose, and HDL metabolism is central in the development of diabetes. We hypothesized that CETP levels would be regulated in diabetic pregnancies. We tested the hypothesis
Chunxiu Hu et al.
PloS one, 6(5), e19423-e19423 (2011-05-26)
Lipids are known to play crucial roles in the development of life-style related risk factors such as obesity, dyslipoproteinemia, hypertension and diabetes. The first selective cannabinoid-1 receptor blocker rimonabant, an anorectic anti-obesity drug, was frequently used in conjunction with diet
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Instructions
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What type of regression fitting is used for the product MAK106, and what is the method for calculating the pmoles shown in the typical standard curve in table 2?
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