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Merck

SML3484

Biotin-XX-tyramide

≥95% (HPLC), membrane-impermeant biotin label, powder

Sinonimo/i:

1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[6-[[6-[[2-(4-hydroxyphenyl)ethyl]amino]-6-oxohexyl]amino]-6-oxohexyl]-2-oxo-, (3aS,4S,6aR)- (9CI, ACI), Biotin-Ahx-AhxX-phenol, Biotin-Ahx-AhxX-tyramide, Biotin-LC-LC-tyramide, Biotin-XX-Tyr; BxxP, Biotin-XX-phenol

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C30H47N5O5S
Numero CAS:
Peso molecolare:
589.79
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
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Nome del prodotto

Biotin-XX-tyramide, ≥95% (HPLC)

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

storage temp.

-10 to -25°C

Quality Level

Categorie correlate

Biochem/physiol Actions

Biotin-XX-tyramide (biotin-XX-phenol; BxxP) is a membrane-impermeant variant of the proximity labeling probe biotin-tyramide (biotin-phenol; BP) that corresponds to BP with a long and polar polyamide linker. Similary to BP, BxxP gives robust biotinylation with HRP and H2O2, but unlike BP, BxxP no longer enters cells, yielding selective labeling of cell surface, but not intracellular, proteins.
Membrane-impermeant variant of biotin-phenol biotin-tyramide (biotin-phenol; BP) for proximity labeling of cell surface, but not intracellular, proteins.

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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The use of biotin or biotin-containing reagents is an essential component of many protein purification and labeling technologies. Owing to its small size and high affinity to the avidin family of proteins, biotin is a versatile molecular handle that permits
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Molecular interactions at the cellular interface mediate organized assembly of single cells into tissues and, thus, govern the development and physiology of multicellular organisms. Here, we developed a cell-type-specific, spatiotemporally resolved approach to profile cell-surface proteomes in intact tissues. Quantitative
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