HNDGAB-220K

MILLIPLEX^® Human Neurodegenerative Autoantibody Magnetic Bead Panel

Simultaneously analyze up to 25 autoantibodies in a bead-based assay using Luminex^® technology, in human serum, plasma, and cerebrospinal fluid (CSF)

• Synonym(e): Luminex^® neuro autoantibody assay, Luminex^® neurodegenerative autoantibody assay, Millipore neuro autoantibody panel, Millipore neurodegenerative autoantibody panel, neuro autoantibody kit, neuro autoantibody multiplex kit, neurodegenerative autoantibody kit
• UNSPSC-Code: 41116126

Eigenschaften

• Qualitätsniveau: 200
• Qualität: 200
• Speziesreaktivität: human
• Hersteller/Markenname: Milliplex^®
• Methode(n): multiplexing: suitable
• Aufnahme: serum; plasma
• Nachweisverfahren: fluorometric (Luminex^® xMAP^® technology)
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

Neurodegenerative autoantibodies are immune system-produced antibodies that mistakenly attack the body′s own nervous system proteins, disrupting synaptic function and causing inflammation and neuronal damage. They target essential proteins like synaptic proteins, neuronal antigens, cell surface receptors, and aggregation-prone proteins. Detecting these autoantibodies in blood or cerebrospinal fluid (CSF) can provide valuable insights into the autoimmune processes linked to neurodegenerative diseases. Research on autoantibodies enhances our understanding of serious neurological disorders and may lead to new therapeutic options.

Anwendung

MILLIPLEX^® Qualified assays undergo rigourous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 25 neurodegenerative autoantibodies in human serum, plasma, and CSF.

Analytes included: anti-α-synuclein, anti-AChR (acetylcholine receptor), anti-AGNA (Anti-Glial Nuclear Antibody, SOX1), anti-Ago2 (Su), anti-CRYAB (α B-crystallin), anti-AMPA-R, anti-Amphiphysin, anti-ANNA2 (Ri)/NOVA1, anti-AQP4 (aquaporin-4), anti-Aβ42, anti-CRMP5 (Collapsin Response Mediater Protein 5), anti-DPPX, anti-DRD2 (Dopamine D2 Receptor), anti-ELAVL4 (HuD), anti-GFAP (Glial Fibrillary Acidic Protein), anti-MBP (Myelin Basic Protein), anti-C1q, anti-mGluR1, anti-MOG (Myelin Oligodendrocyte Glycoprotein), anti-NF-L (Neurofilament light chain), anti-NMDAR1, anti-NRXN3 (neurexin-3), anti-PCA1 (Yo)/CDR2, anti-PNMA1 (Ma1), and anti-tTau

Assay Characteristics: Refer to kit protocol for assay cross-reactivity and sensitivity.

Leistungsmerkmale und Vorteile

• Versatile Analyte Selection: Customize your research with the ability to select from a panel of 25 neurodegenerative autoantibodies, allowing for tailored solutions that address specific research questions.
• All-in-One Kit Format: Each kit includes all necessary reagents and an intuitive protocol, simplifying the assay process and reducing the need for multiple kits, which saves time and resources.
• High Precision and Specificity: Achieve reliable results with demonstrated precision (<10% intra-assay CV and <15% inter-assay CV) and minimal cross-reactivity, ensuring the accuracy and trustworthiness of your findings.
• Unique Neurodegenerative Disease Research Tool: This first-of-its-kind assay enables valuable insights into the autoimmune mechanisms underlying neurodegenerative diseases.

Angaben zur Herstellung

Recommended storage for kit components is 2-8˚C.

Rechtliche Hinweise

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp