The storage temperature and solution stability after reconstitution in DMSO have not been tested. It is recommended to make the solution fresh upon usage.
P1793
Pimozide
≥98% (TLC), powder, D₂ dopamine receptor antagonist
Sinónimos:
1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
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Acerca de este artículo
Fórmula empírica (notación de Hill):
C28H29F2N3O
Número CAS:
Peso molecular:
461.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
218-171-7
MDL number:
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Servicio técnico
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Permítanos ayudarleNombre del producto
Pimozide,
InChI key
YVUQSNJEYSNKRX-UHFFFAOYSA-N
InChI
1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
SMILES string
Fc1ccc(cc1)C(CCCN2CCC(CC2)N3C(=O)Nc4ccccc34)c5ccc(F)cc5
form
powder
solubility
DMSO: 18 mg/mL(lit.)
chloroform: 5 mg/mL
H2O: insoluble(lit.)
originator
Teva
storage temp.
2-8°C
Quality Level
Gene Information
human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Scnn1g(24768)
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Este artículo | P1750000 | BP682 | Y0002391 |
|---|---|---|---|
| form powder | form - | form solid | form - |
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 18 mg/mL(lit.), H2O: insoluble(lit.), chloroform: 5 mg/mL | solubility - | solubility - | solubility - |
| originator Teva | originator - | originator - | originator - |
| Gene Information human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985) | Gene Information human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356) | Gene Information human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356) | Gene Information - |
Biochem/physiol Actions
D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor; Ca2+ channel antagonist; antipsychotic
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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When dissolved in DMSO, at what temperature should I store the solution?
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