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DRD1

dopamine receptor D1

Synonyms:

DADR, DRD1A

Species:

Human DRD1 (1812), Rat Drd1 (24316), Thale Cress DRD1 (816136), dog DRD1 (489110), domestic guinea pig Drd1 (100729180), naked mole-rat Drd1 (101720342), cow DRD1 (281125), sheep DRD1 (100568292), domestic cat DRD1 (101085098), Horse DRD1 (100058846)

UniProtKB ID:

P21728, B2RA44, Q4QRJ0

Gene ID:

Human(1812) Summary: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
Rat(24316) dopamine receptor D1
Thale Cress(816136) putative chromatin remodeling protein
dog(489110) dopamine receptor D1
domestic guinea pig(100729180) dopamine receptor D1
naked mole-rat(101720342) dopamine receptor D1
cow(281125) dopamine receptor D1
sheep(100568292) dopamine receptor D1
domestic cat(101085098) dopamine receptor D1
Horse(100058846) dopamine receptor D1
chicken(427633) dopamine receptor D1

Products (56)
Peer Reviewed Papers (207)

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Small Molecule - Agonist

Product Number

Description

Species

C130

Chloro-APB hydrobromide, solid,

Species

human

A255

A-77636 hydrochloride hydrate, ≥98% (HPLC), solid,

Species

human

S143

(±)-6-Chloro-PB hydrobromide, ≥98% (HPLC), solid,

Species

human

Fenoldopam mesylate, ≥98% (HPLC),

Species

human

Fenoldopam mesylate, United States Pharmacopeia (USP) Reference Standard,

Species

human

Small Molecule - Antagonist

Product Number

Description

Species

D054

R(+)-SCH-23390 hydrochloride, ≥98% (HPLC), solid,

Species

human

Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,

Species

human

Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,

Species

human

Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,

Species

human

T103

Trifluperidol hydrochloride, ,

Species

human

Antibodies

Product Number

Description

Species Reactivity

Application

Anti-Dopamine Receptor D1 Antibody, Chemicon^®, from rabbit,

Species Reactivity

human

Application

immunohistochemistry

Anti-Dopamine D(1A) Receptor Antibody, from rabbit, purified by affinity chromatography,

Species Reactivity

bovine, rat

Application

ELISA
immunohistochemistry
western blot

Anti-Dopamine D1A Receptor Antibody, 4th Extracellular Domain, Chemicon^®, from rabbit,

Species Reactivity

rat

Application

ELISA
immunohistochemistry
western blot

Anti-Dopamine D1 receptor Antibody, clone 2L4 ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,

Species Reactivity

bovine, camel, feline, human, monkey, porcine, rat, sheep

Application

affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

Anti-DRD1 antibody produced in rabbit, affinity isolated antibody,

Species Reactivity

human, mouse, rat

Application

ELISA
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Product Number

Description

Species

D052

GBR 12909 dihydrochloride, solid, ≥98% (HPLC),

Species

human

B102

Bupropion hydrochloride, ≥98% (HPLC), solid,

Species

human

Amoxapine, United States Pharmacopeia (USP) Reference Standard,

Species

human

Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant^®,

Species

human

Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,

Species

human

Small Molecule - Metabolite

Product Number

Description

Species

3-Methoxytyramine hydrochloride, ≥95.5%, crystalline,

Species

human

3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,

Species

human

Small Molecule - Precursor

Product Number

Description

Species

3,4-Dihydroxy-DL-phenylalanine, ,

Species

mouse, human, rat

3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),

Species

mouse, human, rat

Proteins

Product Number

Description

Species

ChemiScreen D₁ Dopamine Receptor Membrane Preparation, Human D1 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,

Species

human

esiRNA

Product Number

Description

Species

MISSION^® esiRNA, targeting human DRD1,

Species

human