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Merck

11009

L-arginina

BioUltra, ≥99.5% (NT)

Sinónimos:

Ácido (S)-2-amino-5-guanidinopentanoico

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Fórmula lineal:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
Número CAS:
Peso molecular:
174.20
Beilstein/REAXYS Number:
1725413
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

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product line

BioUltra

Quality Level

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D +27.0±0.5°, c = 5% in 5 M HCl

impurities

insoluble matter, passes filter test
≤0.3% foreign amino acids

ign. residue

≤0.05% (as SO4)

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

pH

10.5-12.0 (25 °C, 0.5 M in H2O)

mp

222 °C (dec.) (lit.)

solubility

H2O: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.5 M in H2O

UV absorption

λ: 260 nm Amax: ≤0.2
λ: 280 nm Amax: ≤0.1

application(s)

peptide synthesis

SMILES string

N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

InChI key

ODKSFYDXXFIFQN-BYPYZUCNSA-N

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

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Este artículo
A1270000A5006A8094
L-arginina European Pharmacopoeia (EP) Reference Standard

A1270000

L-arginina

form

powder or crystals

form

-

form

powder

form

powder

assay

≥99.5% (NT)

assay

-

assay

≥98%

assay

98.5-101.0%

product line

BioUltra

product line

-

product line

-

product line

BioXtra

color

white

color

-

color

white

color

white

impurities

insoluble matter, passes filter test, ≤0.3% foreign amino acids

impurities

-

impurities

-

impurities

endotoxin, tested

optical activity

[α]20/D +27.0±0.5°, c = 5% in 5 M HCl

optical activity

-

optical activity

-

optical activity

-

Application


  • L-Arginine-Dependent Nitric Oxide Production in the Blood of Patients with Type 2 Diabetes: A Pilot, Five-Year Prospective Study.: This study examines the role of L-Arginine in nitric oxide production in diabetic patients, proposing its potential benefits for managing vascular complications in diabetes (Stoian et al., 2024).

Biochem/physiol Actions

Sustrato de la óxido nítrico sintasa, que se convierte en citrulina y óxido nítrico (NO). Induce la liberación de insulina mediante un mecanismo dependiente del óxido nítrico.

Other Notes

Exhibits stabilizing effects on plant protoplasts[1]; pH drift correction in IEF of proteins[2]; Growth requirement of various microorganisms[3].

Clase de almacenamiento

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

A.W. Galston et al.
Plant Sci. Lett., 11, 69-69 (1978)
CRC Handbook of Microbiology, 4, 1-1 (1974)
H. Delice et al.
Electrophoresis '79, 165-165 (1980)
Krishnan Suresh Kumar et al.
European journal of medicinal chemistry, 45(11), 5474-5479 (2010-08-21)
A new series of 3-(benzylideneamino)-2-phenylquinazoline-4(3H)-ones were prepared through Schiff base formation of 3-amino-2-phenyl quinazoline-4(3)H-one with various substituted carbonyl compounds. Their chemical structures were elucidated by spectral studies. Cytotoxicity and antiviral activity were evaluated against herpes simplex virus-1 (KOS), herpes simplex
Palaniraja Thandapani et al.
Molecular cell, 50(5), 613-623 (2013-06-12)
Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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