C7757

S-Carboxymethyl-L-cysteine

Name: S-Carboxymethyl-<SC>L</SC>-cysteine
Brand: SIGMA

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Fórmula empírica (notación de Hill):

C₅H₉NO₄S

Número CAS:

638-23-3

Peso molecular:

179.19

Beilstein/REAXYS Number:

1725012

EC Number:

211-327-5

MDL number:

MFCD00002614

UNSPSC Code:

12352209

PubChem Substance ID:

24892985

NACRES:

NA.26

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assay

>98% (TLC)

Quality Level

100

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

200 °C

storage temp.

2-8°C

SMILES string

N[C@@H](CSCC(O)=O)C(O)=O

InChI

1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

Inchi Key

GBFLZEXEOZUWRN-VKHMYHEASA-N

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Categorías relacionadas

Amino Acids

Biochemicals

Cell Culture Supplements & Reagents

Chemistry & Biochemicals

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Este artículo	A9165	A8199	M4139
Sigma-Aldrich C7757 S-Carboxymethyl-L-cysteine	Sigma-Aldrich A9165 N-Acetyl-L-cysteine	Sigma-Aldrich A8199 N-Acetyl-L-cysteine	Sigma-Aldrich M4139 S-Methylglutathione
form powder	form powder	form powder	form powder
assay >98% (TLC)	assay ≥99% (TLC)	assay ≥99% (TLC)	assay >98% (TLC)
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
Quality Level 100	Quality Level 200	Quality Level 300	Quality Level 200
mp 200 °C	mp 106-108 °C (lit.)	mp 106-108 °C (lit.)	mp -

Biochem/physiol Actions

S-Carboxymethyl-L-cysteine is studied as a small molecule mucoactive drug in vivo. These studies include analyzing the oxidative metabolism of S-carboxymethyl-L-cysteine by enzymes such as phenylalanine monooxygenase(s).

Clase de almacenamiento

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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The pharmacokinetics of orally administered S-carboxymethyl-L-cysteine in the dog, calf and sheep.

Panayotis Panagopoulos et al.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 39(4), 219-223 (2009-12-29)

The aim of this study was to investigate the feasibility of employing S-carboxymethyl-L-cysteine as a treatment of chronic obstructive pulmonary disease in dogs. To this end the pharmacokinetic parameters of orally administered S-carboxymethyl-L-cysteine were determined in the dog, cow and

Recombinant heteromeric phenylalanine monooxygenase and the oxygenation of carbon and sulfur substrates.

Boonyapiwat B, Mitchell SC, et al.

J. Pharm. Pharm. Sci., 63, 558-564 (2011)

Identification of novel small molecule antimicrobials targeting Mycoplasma bovis.

Marty K Soehnlen et al.

The Journal of antimicrobial chemotherapy, 66(3), 574-577 (2011-03-12)

To screen novel small molecule compounds for inhibition of Mycoplasma bovis growth and to characterize their activity in terms of dose-dependency and ability to function in milk. Using a tetrazolium salt cytotoxicity assay, 480 natural compounds were screened to determine

Human phenylalanine monooxygenase and thioether metabolism.

Boonyapiwat B, Panaretou B, et al.

J. Pharm. Pharm. Sci., 61, 63-67 (2009)

S-carboxymethylcysteine inhibits adherence of Streptococcus pneumoniae to human alveolar epithelial cells.

Tomoko Sumitomo et al.

Journal of medical microbiology, 61(Pt 1), 101-108 (2011-09-06)

Streptococcus pneumoniae is a major pathogen of respiratory infections that utilizes platelet-activating factor receptor (PAFR) for firm adherence to host cells. The mucolytic agent S-carboxymethylcysteine (S-CMC) has been shown to exert inhibitory effects against infection by several respiratory pathogens including

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