Saltar al contenido
Merck

O8010

Okadaic acid ammonium salt

From plant (Prorocentrum concavum), ≥90% (HPLC), type 1 and type 2A protein phosphatases inhibitor, solid

Sinónimos:

OA

Slide 1 of 1
Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

10 μG

MXP 3,227.00

25 μG

MXP 7,061.00

50 μG

MXP 12,239.00

MXP 3,227.00

Comprobar disponibilidad del carrito
Solicite una orden a granel

Acerca de este artículo

Fórmula empírica (notación de Hill):
C44H68O13 · NH3
Número CAS:
155716-06-6
Peso molecular:
822.03
UNSPSC Code:
12352106
PubChem Substance ID:
24898053
NACRES:
NA.77
MDL number:
MFCD00153856

Documentos clave

Ver Toda la documentación

Saltar a

Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle

Nombre del producto

Okadaic acid ammonium salt from Prorocentrum concavum, ≥90% (HPLC), solid

SMILES string

[H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O

InChI key

ZBOMSHVRJSJGNR-JBNKPAQWSA-N

InChI

1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1

biological source

plant (Prorocentrum concavum)

assay

≥90% (HPLC)

form

solid

color

white

solubility

H2O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

Quality Level

200

Categorías relacionadas

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 4

Este artículo
O7760O9381D5794
Okadaic acid ammonium salt from Prorocentrum concavum ≥90% (HPLC), solid

Sigma-Aldrich

O8010

Okadaic acid ammonium salt from Prorocentrum concavum

Okadaic acid sodium salt from Prorocentrum concavum ≥90% (HPLC), film

Sigma-Aldrich

O7760

Okadaic acid sodium salt from Prorocentrum concavum

Okadaic acid from Prorocentrum concavum 92-100% (HPLC)

Sigma-Aldrich

O9381

Okadaic acid from Prorocentrum concavum

Diacylglycerol Kinase Inhibitor II solid

Sigma-Aldrich

D5794

Diacylglycerol Kinase Inhibitor II

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

92-100% (HPLC)

assay

≥97% (HPLC)

form

solid

form

film

form

powder

form

solid

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 0.1 mg/mL, ethanol: soluble, DMSO: soluble

solubility

0.1% acetic acid in CH3CN: H2O (1:1): 250 μg/mL, clear, colorless

solubility

DMSO: ≥1 mg/mL, ethanol: ≥1 mg/mL, methanol: ≥1 mg/mL, H2O: insoluble

solubility

0.1 M HCl: slightly soluble, 0.1 M NaOH: slightly soluble, DMSO: soluble, H2O: insoluble, ethanol: soluble, ethyl acetate: soluble

color

white

color

translucent

color

-

color

pale yellow

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
SLCN4651
SLCF6121
SLCD0695
SLCC9868
SLBZ9425

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Li-Ping Nan et al.
Connective tissue research, 61(6), 554-567 (2019-07-12)
Purpose: To investigate the protective effect of naringin (Nar) on H2O2-induced apoptosis of nucleus pulposus-derived mesenchymal stem cells (NPMSC) and the potential mechanism in this process. Methods: Rat NPMSC were cultured in MSC culture medium or culture medium with different
Shao-Chih Chiu et al.
Journal of cellular physiology, 237(1), 1033-1043 (2021-09-21)
The Golgi apparatus (GA) translocates to the cell leading end during directional migration, thereby determining cell polarity and transporting essential factors to the migration apparatus. The study provides mechanistic insights into how GA repositioning (GR) is regulated. We show that
Yun-Ling He et al.
Cell death & disease, 13(11), 966-966 (2022-11-18)
Mitophagy is an important metabolic mechanism that modulates mitochondrial quality and quantity by selectively removing damaged or unwanted mitochondria. BNIP3 (BCL2/adenovirus e1B 19 kDa protein interacting protein 3), a mitochondrial outer membrane protein, is a mitophagy receptor that mediates mitophagy under
Dong-Keon Kim et al.
Cancers, 12(9) (2020-09-17)
Octamer-binding transcription factor 4 (Oct4) plays an important role in maintaining pluripotency in embryonic stem cells and is closely related to the malignancies of various cancers. Although posttranslational modifications of Oct4 have been widely studied, most of these have not
Xufeng Chen et al.
Cell, 186(18), 3903-3920 (2023-08-10)
Immune-checkpoint blockade has revolutionized cancer treatment, but some cancers, such as acute myeloid leukemia (AML), do not respond or develop resistance. A potential mode of resistance is immune evasion of T cell immunity involving aberrant major histocompatibility complex class I (MHC-I)
Ver todos los artículos relacionados

Questions

Reviews

No rating value

Active Filters

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico