1.00030

Acetonitrile

≥99.9% (GC), gradient grade, suitable for HPLC, Reag. Ph Eur, LiChrosolv^®

• Synonym(s): ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
• Linear Formula: CH₃CN
• CAS Number: 75-05-8
• Molecular Weight: 41.05
• Beilstein: 741857
• MDL number: MFCD00001878
• UNSPSC Code: 12191502
• EC Index Number: 200-835-2
• NACRES: NA.03
• Grade: gradient grade
• Assay: ≥99.9% (GC); ≥99.9%
• Technique(s): HPLC: suitable
• Bp: 81-82 °C (lit.)
• Vapor pressure: 72.8 mmHg ( 20 °C); 97 hPa ( 20 °C)

Properties

• Product Name: Acetonitrile, gradient grade for liquid chromatography LiChrosolv^® Reag. Ph Eur
• grade: gradient grade
• Quality Level: 200
• Agency: reag. Ph. Eur.
• vapor density: 1.41 (vs air)
• vapor pressure: 72.8 mmHg ( 20 °C); 97 hPa ( 20 °C)
• description: (Absorbance (at 200 nm) <=0.1; ; ; Absorbance (from 240 nm) <=0.01)
• product line: LiChrosolv^®
• Assay: ≥99.9% (GC); ≥99.9%
• form: liquid
• autoignition temp.: 524 °C; 973 °F
• expl. lim.: 16 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.02% Water
• evapn. residue: ≤2.0 mg/L
• color: APHA: ≤10
• transmittance: 193 nm, ≥60%; 195 nm, ≥80%; 230 nm, ≥98%
• refractive index: n/D 1.344; n20/D 1.344 (lit.)
• bp: 81-82 °C (lit.)
• mp: −45 °C (lit.)
• transition temp: flash point 2 °C
• density: 0.786 g/mL at 25 °C (lit.); 0.78-20 °C
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• InChI key: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Description

General description

LiChrosolv^® solvents were specially formulated to meet the demanding needs of analytical HPLC applications. With exceptional UV transmittance, minimal particle count, and controlled acidity and alkalinity, our solvents ensure reproducible separations every time. The low evaporation residue level further enhances their performance, making them the ideal choice for high-quality results. The product line includes both "gradient grade" and "isocratic grade" solvents, specifically designed to reduce the gradient effect during separations. This tailored approach allows for optimal consistency and accuracy in your analytical processes, helping you achieve the best possible outcomes in your chromatography work.

Now Available with Data Matrix Code
This high-quality HPLC-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.
Know more about our data matrix code-labeled HPLC-grade solvents.

Application

• Reversed-Phase HPLC: Commonly used as a mobile phasecomponent for the separation of a wide range of compounds, includingpharmaceuticals, environmental pollutants, and biomolecules.
• Gradient Elution: Ideal for gradient elutiontechniques, enhancing the resolution and separation efficiency of complexmixtures.
• Pharmaceutical Analysis: Frequently employed in theanalysis of active pharmaceutical ingredients (APIs) and their impurities,ensuring compliance with regulatory standards.
• Biological Sample Analysis: Used for the analysis ofproteins, peptides, and metabolites in biological samples, facilitatingaccurate quantification and identification.
• Environmental Monitoring: Applied in the HPLCanalysis of environmental samples to detect and quantify contaminants in water,soil, and air.

Features and Benefits

• High Purity: Formulated with minimal impurities, ensuring reliable and reproducible results essential for sensitive analytical applications.
• Excellent UV Transparency: Provides optimal UV transmittance, facilitating accurate detection and enhancing sensitivity in HPLC analyses.
• Low Evaporation Residue: Minimizes contamination risk, leading to cleaner separations and improved analytical reliability.
• Batch-to-Batch Consistency: Ensures uniform quality and performance across different production batches, enhancing reproducibility and confidence in analytical results.

Preparation Note

Microfiltered by 0.2 μm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2.0 °C - closed cup