39380

3-(Dimethylamino)-1-propylamine

purum, ≥98.0% (GC)

• Synonym(s): N,N-Dimethyl-1,3-diaminopropane, N,N-Dimethyl-1,3-propanediamine
• Linear Formula: (CH₃)₂N(CH₂)₃NH₂
• CAS Number: 109-55-7
• Molecular Weight: 102.18
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 329755864
• EC Number: 203-680-9
• Beilstein/REAXYS Number: 605293
• MDL number: MFCD00008216

Properties

• Product Name: 3-(Dimethylamino)-1-propylamine, purum, ≥98.0% (GC)
• InChI key: IUNMPGNGSSIWFP-UHFFFAOYSA-N
• InChI: 1S/C5H14N2/c1-7(2)5-3-4-6/h3-6H2,1-2H3
• SMILES string: CN(C)CCCN
• vapor density: 3.6 (vs air)
• vapor pressure: 5 mmHg ( 20 °C)
• grade: purum
• assay: ≥98.0% (GC)
• form: liquid
• impurities: ≤2% water
• refractive index: n20/D 1.435 (lit.); n20/D 1.436
• bp: 133 °C (lit.)
• density: 0.812 g/mL at 25 °C (lit.)
• functional group: amine
• Quality Level: 200

Description

Application

3-(Dimethylamino)-1-propylamine (DMAPA) is suitable reagent used in the following studies:

• As a cationic moiety to form the ionic liquid, 3-(dimethylamino)-1-propylaminium formate ([DMAPA]FA) which is a potential reagent to extract protein from yeast cells.[1]
• As an aminating agent in the palladium-catalyzed amination of aryl amines.[2]
• In the derivatization of pullulan to form cationic pullulan.[3]
• In the partial modification of poly(styrene-alt-maleic anhydride) to form N-substituted maleimide.[4]
• As a test compound in the parallel synthesis of alkylamine lipidoids.[5]
• To cleave the polyamides synthesized by solid phase methods on Boc-β-Ala-PAM resin.[6]

It may be used in the following studies:

• Synthesis of (N,N-dialkylamino)alkyl-2-amino benzamide by reacting with isatoic anhydride.[7]
• As a reagent for the anomeric deacetylation of protected sugars.[8]
• Preparation of bioreducible copolymers used in gene delivery.[9]

General description

3-(Dimethylamino)-1-propylamine (DMAPA, N,N-dimethyl-1,3-propanediamine)[1] is a dialkylamino alkyl amine.[7] It has been prepared from dimethylamine and acrylonitrile and confirmed by ¹H NMR.[10] It participates in the synthesis of bio-based zwitterionic surfactants from waste cooking oil (WCO).[11]

Other Notes

Industrial applications[12]

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H226,H302 + H312,H314,H317,H335
• pcodes: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: 89.6 °F - closed cup
• flash_point_c: 32 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter