Citric acid

Name: Citric acid
Brand: SIGMA

BioUltra, anhydrous, ≥99.5% (T)

Slide 1 of 1

Select a Size

Pricing and availability is not currently available.

About This Item

Linear Formula:

HOC(COOH)(CH₂COOH)₂

CAS Number:

77-92-9

Molecular Weight:

192.12

NACRES:

NA.25

PubChem Substance ID:

57648248

eCl@ss:

39021801

UNSPSC Code:

12161700

EC Number:

201-069-1

MDL number:

MFCD00011669

Beilstein/REAXYS Number:

782061

Key Documents

View All Documentation

Product Name

Citric acid, BioUltra, anhydrous, ≥99.5% (T)

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

grade

biotech. grade

product line

BioUltra

assay

≥99.5% (T)

form

powder or crystals

expl. lim.

8 %, 65 °F

technique(s)

cell culture | hybridoma: suitable

impurities

insoluble matter, passes filter test

ign. residue

≤0.05% (as SO₄)

loss

≤0.5% loss on drying, 110 °C

pH

1.0-2.0 (25 °C, 1 M in H₂O)

pKa

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

solubility

H₂O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl^-): ≤5 mg/kg
oxalate (C₂O₄^2-): ≤0.05%
phosphate (PO₄^3-): ≤5 mg/kg
sulfate (SO₄^2-): ≤20 mg/kg
tartrate (C₄H₄O₆^2-): ≤0.20%

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ_max

260 nm (Amax: ≤0.20)
280 nm (Amax: ≤0.10)

λ

1 M in H₂O

UV absorption

λ: 260 nm A_max: 0.20
λ: 280 nm A_max: 0.10

Quality Level

200

Gene Information

human ... SRC(6714)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochemicals

Biological Buffers

High-Purity Biochemicals and Reagents

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	251275	C2404	W230618
Sigma-Aldrich 27487 Citric acid	Sigma-Aldrich 251275 Citric acid	Sigma-Aldrich C2404 Citric acid	Sigma-Aldrich W230618 Citric acid
assay ≥99.5% (T)	assay ≥99.5%	assay ≥97% (GC)	assay ≥99.5%
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 400
form powder or crystals	form crystals	form powder	form powder or granules
pH 1.0-2.0 (25 °C, 1 M in H₂O)	pH -	pH 1.8 (25 °C, 50 g/L)	pH -
solubility H₂O: 1 M at 20 °C, clear, colorless	solubility -	solubility water: 50 mg/mL, clear to very slightly hazy, colorless	solubility water: 383 g/L at 25 °C
cation traces Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Sr: ≤5 mg/kg, As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Mn: ≤5 mg/kg, Pb: ≤5 mg/kg, Bi: ≤5 mg/kg, Li: ≤5 mg/kg, Zn: ≤5 mg/kg, Cr: ≤5 mg/kg, Na: ≤50 mg/kg	cation traces Fe: ≤3 ppm, Pb: ≤2 ppm	cation traces -	cation traces As: ≤3.0 ppm, Cd: ≤1.0 ppm, Hg: ≤1.0 ppm, Pb: ≤0.5 ppm

Application

Enhancing soil microbiomes: Citric acid has been applied to modify soil bacterial communities in saline mudflats, demonstrating its utility in environmental biotechnology for sustainable ecosystem management (Liu et al., 2024).

Biodegradable packaging in food industry: In food chemistry, citric acid is used in conjunction with polyvinyl alcohol for developing antimicrobial packaging, highlighting its potential in food safety and preservation (Xu et al., 2024).

Nanomaterial synthesis for engineering applications: Citric acid serves as a key component in the eco-friendly synthesis of hybrid nanomaterials for supercapacitors, underpinning its role in advancing materials science and engineering (Teixeira et al., 2024).

Environmental science and pollution control: Research utilizes citric acid to study the co-transport of pharmaceuticals and nanoparticles in environmental systems, aiding in the understanding of contaminant dynamics and mitigation strategies (Cui et al., 2024).

Food science and technology: Citric acid is employed in the formulation of vegan gummies, indicating its versatility in food product development and its impact on textural properties (Rawat et al., 2024).

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to the US EPA′s Federal Insecticide Fungicide and Rodenticide Act, the European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR), and others.

General description

Citric acid is a buffer component for triple-column amino acid analysis.[1] It is an optimal buffer for dissociation of radioiodinated antibodies from viable murine tumor cells.[2]

pictograms

GHS07

signalword

Warning

hcodes

H319,H335

pcodes

P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Triple-column ion-exchange physiological amino acid analysis with fluorescent detection: baseline characterization of human cerebrospinal fluid.

T N Ferraro et al.

Analytical biochemistry, 143(1), 82-94 (1984-11-15)

A highly resolving triple-column amino acid analyzer with fluorometric detection is described. The reliability of this technique was evaluated and it was used in a baseline investigation of amino acids and related compounds in human cerebrospinal fluid (CSF). The procedure

The elution of antibodies from viable murine tumor cells.

R Ehrlich et al.

Journal of immunological methods, 26(4), 345-353 (1979-01-01)

Several low pH buffers were used in order to dissociate radioiodinated antibodies from sensitized living tumor cells. Three buffers were further tested for their dissociation abilities under different conditions of time and temperature, and for their influence on the eluted

Structure-guided residence time optimization of a dabigatran reversal agent.

Felix Schiele et al.

mAbs, 7(5), 871-880 (2015-06-06)

Novel oral anticoagulants are effective and safe alternatives to vitamin-K antagonists for anticoagulation therapy. However, anticoagulation therapy in general is associated with an elevated risk of bleeding. Idarucizumab is a reversal agent for the direct thrombin inhibitor, dabigatran etexilate (Pradaxa®)

Mononuclear cell secretome protects from experimental autoimmune myocarditis.

Konrad Hoetzenecker et al.

European heart journal, 36(11), 676-685 (2013-01-17)

Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients.

New molecular staging with G-factor supplements TNM classification in gastric cancer: a multicenter collaborative research by the Japan Society for Gastroenterological Carcinogenesis G-Project committee.

Tetsuji Sawada et al.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 18(1), 119-128 (2014-02-04)

The G-Project committee was erected by the Japan Society for Gastroenterological Carcinogenesis with an aim of establishing a new classification scheme based on molecular biological characteristics that would supplement the conventional TNM classification to better predict outcome. In a literature

View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service