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Rotenone
PESTANAL®, analytical standard
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
250 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 189,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C23H22O6
Numer CAS:
Masa cząsteczkowa:
394.42
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-501-9
Beilstein/REAXYS Number:
6773081
MDL number:
189,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Pozwól nam pomócgrade
analytical standard
Quality Segment
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
bp
210-220 °C/0.5 mmHg (lit.)
mp
159-164 °C (lit.)
application(s)
agriculture
environmental
format
neat
SMILES string
COc1cc2OCC3Oc4c5C[C@@H](Oc5ccc4C(=O)C3c2cc1OC)C(C)=C
InChI
1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1
InChI key
JUVIOZPCNVVQFO-HBGVWJBISA-N
General description
Rotenone is a contact insecticide and a slow stomach poison, extremely potent against many insects. It is widely used against Varroa Jacobsoni mite, affecting colonies of honey bees.
Application
Rotenone may be used as an analytical reference standard for the quantification of the analyte in raw honey samples and biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Inhibitor of mitochondrial electron transport.
Rotenone is an inhibitor of mitochondrial electron transport at nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone acts as a neurotoxic agent which can produce Parkinson-like condition to serve as an animal model for the study of etiology and interventions. The primary mechanism of action of rotenone is complex I inhibition, followed by the generation of oxidative stress and oxidative damage. Because rotenone is lipophilic, it readily penetrates the brain, where it attaches to and inhibits mitochondrial complex I of electron chain transport (ETC).
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja | |||
|---|---|---|---|
| description PESTANAL®, analytical standard | description certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | description ≥95% | description A mitochondrial toxin and a potent, reversible, and competitive inhibitor of complex I (NADH-CoQ reductase) of the respiratory chain. |
| format neat | format - | format - | format - |
| technique(s) gas chromatography (GC): suitable, HPLC: suitable | technique(s) - | technique(s) - | technique(s) - |
| grade analytical standard | grade certified reference material, TraceCERT® | grade - | grade - |
| product line PESTANAL® | product line TraceCERT® | product line - | product line - |
| bp 210-220 °C/0.5 mmHg (lit.) | bp 210-220 °C/0.5 mmHg (lit.) | bp 210-220 °C/0.5 mmHg (lit.) | bp - |
| application(s) agriculture | application(s) - | application(s) - | application(s) - |
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Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Klasa składowania
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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