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Merck

PHR1096

L-Lysine Acetate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

L-Lysine acetate salt, (S)-2,6-Diaminohexanoic acid

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C6H14N2O2 · C2H4O2
Numer CAS:
57282-49-2
Masa cząsteczkowa:
206.24
NACRES:
NA.24
PubChem Substance ID:
329823118
UNSPSC Code:
41116107
MDL number:
MFCD00039069

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Nazwa produktu

L-Lysine Acetate, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C6H14N2O2.C2H4O2/c7-4-2-1-3-5(8)6(9)10;1-2(3)4/h5H,1-4,7-8H2,(H,9,10);1H3,(H,3,4)/t5-;/m0./s1

SMILES string

CC(O)=O.NCCCC[C@H](N)C(O)=O

InChI key

RRNJROHIFSLGRA-JEDNCBNOSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000397
traceable to USP 1371501

API family

lysine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. L-Lysine is an essential proteinogenic α-amino acid, containing basic side chain and is hydrophilic in nature. L-Lysine is actively used in the form of its acetate salt. It serves as a precursor for secondary metabolites, such as β-lactam antibiotics. It also serves as a precursor for the biosynthesis of α-aminoadipic acid.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7162 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.
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Klasa składowania

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

In the matter of certain amino acid formulations: unreviewed initial determination (1983)
Lubin Jiang et al.
Nature, 499(7457), 223-227 (2013-07-05)
The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), which is expressed on the surface of P. falciparum-infected red blood cells, is a critical virulence factor for malaria. Each parasite has 60 antigenically distinct var genes that each code
Juan Li et al.
Poultry science, 92(6), 1683-1689 (2013-05-21)
The objective of this experiment was to evaluate the effect of dietary lysine concentration on meat quality and carcass traits in 2 chicken lines, SD02 and SD03, and their crosses, both originating from a Chinese native breed, the Erlang Mountainous
Jeongsoon Park et al.
Molecular cell, 50(6), 919-930 (2013-06-29)
Protein function is regulated by diverse posttranslational modifications. The mitochondrial sirtuin SIRT5 removes malonyl and succinyl moieties from target lysines. The spectrum of protein substrates subject to these modifications is unknown. We report systematic profiling of the mammalian succinylome, identifying
Samir Zaidi et al.
Nature, 498(7453), 220-223 (2013-05-15)
Congenital heart disease (CHD) is the most frequent birth defect, affecting 0.8% of live births. Many cases occur sporadically and impair reproductive fitness, suggesting a role for de novo mutations. Here we compare the incidence of de novo mutations in
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