91228

Trichloroacetic acid

BioUltra, ≥99.5% (T)

• Synonim(y): TCA
• Wzór liniowy: Cl₃CCOOH
• Numer CAS: 76-03-9
• Masa cząsteczkowa: 163.39
• UNSPSC Code: 12352101
• NACRES: NA.25
• PubChem Substance ID: 57653428
• EC Number: 200-927-2
• Beilstein/REAXYS Number: 970119
• MDL number: MFCD00004177
• eCl@ss: 32150313
• Assay: ≥99.5% (T)
• Form: crystals, flakes
• Grade: biotech. grade

Właściwości

• grade: biotech. grade
• Quality Segment: 200
• vapor density: <1 (vs air)
• vapor pressure: 1 mmHg ( 51 °C)
• product line: BioUltra
• assay: ≥99.5% (T)
• form: crystals, flakes
• impurities: insoluble matter, passes filter test
• ign. residue: ≤0.05%
• refractive index: n20/D 1.62 (lit.)
• pH: <1.0 (25 °C, 0.5 M in H₂O)
• bp: 196 °C (lit.)
• mp: 54-58 °C (lit.)
• solubility: H₂O: 0.5 M at 20 °C, clear, colorless
• density: 1.62 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤30 mg/kg, nitrate (NO₃^-): ≤20 mg/kg, phosphate (PO₄^3-): ≤10 mg/kg, sulfate (SO₄^2-): ≤100 mg/kg
• SMILES string: OC(=O)C(Cl)(Cl)Cl
• cation traces: Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
• λ: 0.5 M in H₂O
• UV absorption: λ: 260 nm A_max: 1.60, λ: 280 nm A_max: 0.15
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: YNJBWRMUSHSURL-UHFFFAOYSA-N

Opis

General description

Trichloroacetic acid (TCA) is derived from Trichloroethylene (TCE) metabolism. It is used as an acid decalcifying agent. TCA is used as a fixative for nuclear staining and protein precipitation.

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Trichloroacetic acid (TCA) has been used:

• to determine its effect on avian embryos during an exposure window encompassing cardiac specification
• as a cell fixative
• to terminate the O-acetylserine (thiol)lyase (OASTL) enzymatic assay
• for the precipitation of acidic ribosomal proteins (RPs)

Other Notes

Concentration of protein by quantitative precipitation; Cytochemical demonstration of DNA with a thiazine dye.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05,GHS09
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H314,H410
• Ostrzeżenia: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• WGK: WGK 2
• Temperatura zapłonu (°F): >235.4 °F - closed cup
• Temperatura zapłonu (°C): > 113 °C - closed cup
• PPE (środki ochrony indywidualnej): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
• Klasa składowania: 8A - Combustible corrosive hazardous materials