The enantiomeric purity of this compound is not a product specification determined for batch release. However, the range of optical rotation value needed for batch release, as indicated in the lot specific Certificate of Analysis, is very close to the published literature value for the (-) enantiomer (Org Lett. 2005 Sep 15;7(19):4181-3).
Przejdź do
C1112
CP-55940
>98% (HPLC), cannabinoid receptor agonist, powder
Synonim(y):
5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
10 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1310,00 zł |
50 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 5100,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C24H40O3
Numer CAS:
Masa cząsteczkowa:
376.57
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
>98% (HPLC)
Form:
powder
Storage condition:
desiccated
1310,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócNazwa produktu
CP-55940, >98% (HPLC), powder
Quality Segment
assay
>98% (HPLC)
form
powder
optical activity
[α]/D -24 to -30°, c = 0.2 in chloroform-d
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
storage condition
desiccated
solubility
DMSO: 15 mg/mL, H2O: slightly soluble
storage temp.
2-8°C
SMILES string
CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
InChI
1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
InChI key
YNZFFALZMRAPHQ-SYYKKAFVSA-N
Gene Information
human ... CNR1(1268), CNR2(1269)
rat ... Cnr1(25248)
Application
CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).
Biochem/physiol Actions
CP-55940 is a selective cannabinoid receptor agonist.
CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.
Features and Benefits
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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Ta pozycja | |||
|---|---|---|---|
| description >98% (HPLC), powder | description 1.0 mg/mL in methanol, analytical standard, for drug analysis | description affinity isolated antibody, buffered aqueous solution | description ≥98%, ethanol solution |
| assay >98% (HPLC) | assay - | assay - | assay ≥98% |
| form powder | form - | form buffered aqueous solution | form ethanol solution |
| drug control regulated under CDSA - not available from Sigma-Aldrich Canada | drug control - | drug control - | drug control - |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −70°C | storage temp. −20°C |
| storage condition desiccated | storage condition - | storage condition - | storage condition - |
Słowo ostrzegawcze
Warning
Kody zagrożeń
Hazard Classifications
STOT SE 3
Narządy docelowe
Respiratory system
Klasa składowania
11 - Combustible Solids
Co się dzieje?
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
PPE (środki ochrony indywidualnej)
Eyeshields, Gloves, type N95 (US)
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Can you please specify whether C1112 (CP 55,940) is a +, a -, or +/- (racemic) enantiomer?
1 answer-
Helpful?
-
-
Could you please specify whether C1112 (CP 55,940) is a +, a -, or +/- (racemic) enantiomer? Thank you!
1 answer-
The enantiomeric purity of this compound is not a product specification determined for batch release. However, the range of optical rotation required for batch release, as indicated in the lot-specific Certificate of Analysis, is very close to the published literature value for the (-) enantiomer.
Org Lett. 2005 Sep 15;7(19):4181-3.
Helpful?
-