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Merck

D2438

Dimethyl sulfoxide

sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

Dimethyl sulfoxide

Synonim(y):

DMSO

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Wybierz wielkość

50 ML

976,00 zł

5 X 10 ML

1020,00 zł

976,00 zł


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Informacje o tej pozycji

Wzór liniowy:
(CH3)2SO
Numer CAS:
Masa cząsteczkowa:
78.13
Beilstein:
506008
Numer WE:
Numer MDL:
Kod UNSPSC:
12191502
Identyfikator substancji w PubChem:
NACRES:
NA.75
Bp:
189 °C (lit.)

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klasa czystości

BioPerformance Certified

Poziom jakości

agency

USP XXIV
meets EP testing specifications
meets USP testing specifications

gęstość pary

2.7 (vs air)

ciśnienie pary

0.42 mmHg ( 20 °C)

sterylność

sterile-filtered

Formularz

liquid

temp. samozapłonu

573 °F

granice wybuchowości

42 %, 63 °F

metody

cell culture | hybridoma: suitable
cryopreservation: suitable

zanieczyszczenia

≤0.1% water

kolor

colorless

współczynnik refrakcji

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

rozpuszczalność

H2O: miscible (completely)

gęstość

1.10 g/mL (lit.)

ciąg SMILES

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

Klucz InChI

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Ta pozycja
41640-M3486934943-M
Quality Level

400

Quality Level

-

Quality Level

100

Quality Level

-

grade

BioPerformance Certified

grade

ACS reagent, puriss. p.a.

grade

-

grade

-

technique(s)

cell culture | hybridoma: suitable, cryopreservation: suitable

technique(s)

-

technique(s)

HPLC: suitable

technique(s)

-

solubility

H2O: miscible (completely)

solubility

-

solubility

-

solubility

-

form

liquid

form

liquid

form

liquid

form

liquid

vapor pressure

0.42 mmHg ( 20 °C)

vapor pressure

0.42 mmHg ( 20 °C)

vapor pressure

0.42 mmHg ( 20 °C)

vapor pressure

0.42 mmHg ( 20 °C)

Opis ogólny

Dimethyl sulfoxide (DMSO) is an aprotic solvent. Therapeutic and toxic molecules that are not soluble in water are often soluble in DMSO. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. DMSO is used to prepare stock solutions of various molecules and is also used as a control for these molecules. It has been used in cell migration assay for dissolving post-migration cells. BPC-tested DMSO also meets the requirements of biotechnology and tissue engineering applications.

Zastosowanie

Dimethyl sulfoxide has been used as a vehicle control to culture and induce hepatic stellate cells (HSCs) activation in vivo.[1][1] It has also been used to prepare a stock solution to study the cytotoxicity of ferulic acid (FA) on nucleus pulposus (NP) cells.[2]

Cechy i korzyści

Ready-to-use sterile filtered product conveniently packaged in septum screw-capped amber bottles. Meets USP and EP testing requirements

Oświadczenie o zrzeczeniu się odpowiedzialności

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

188.6 °F - closed cup

Temperatura zapłonu (°C)

87 °C - closed cup

Środki ochrony indywidualnej

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Certyfikaty analizy (CoA)

Lot/Batch Number

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

A Oguro-Ando et al.
Molecular psychiatry, 20(9), 1069-1078 (2014-10-15)
Rare maternally inherited duplications at 15q11-13 are observed in ~1% of individuals with an autism spectrum disorder (ASD), making it among the most common causes of ASD. 15q11-13 comprises a complex region, and as this copy number variation encompasses many
Caroline Godfrey et al.
Human molecular genetics, 24(15), 4225-4237 (2015-05-03)
Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of dystrophin protein. Despite this, the relationship between restoring dystrophin to established dystrophic muscle and its ability to induce clinically relevant changes in muscle
C F Brayton
The Cornell veterinarian, 76(1), 61-90 (1986-01-01)
Dimethyl sulfoxide (DMSO) is a very simple compound that has stimulated much controversy in the scientific and popular literature. Fig. 1 It is an aprotic solvent. Therapeutic and toxic agents that are not soluble in water are often soluble in
Björn Zörner et al.
Brain : a journal of neurology, 137(Pt 6), 1716-1732 (2014-04-17)
Anatomical plasticity such as fibre growth and the formation of new connections in the cortex and spinal cord is one known mechanism mediating functional recovery after damage to the central nervous system. Little is known about anatomical plasticity in the
Mulmudi Hemant Kumar et al.
Advanced materials (Deerfield Beach, Fla.), 26(41), 7122-7127 (2014-09-13)
Lead free perovskite solar cells based on a CsSnI3 light absorber with a spectral response from 950 nm is demonstrated. The high photocurrents noted in the system are a consequence of SnF2 addition which reduces defect concentrations and hence the

Produkty

Przegląd dobrych praktyk bankowania komórek do celów kriokonserwacji linii komórkowych.

Overview of good cell banking practices for cell line cryopreservation purposes.

Questions

1–10 of 16 Questions  
  1. For D2438-5X10ML, do they come in glass ampoule or bottle with lid?

    1 answer
    1. Yes, both package sizes have a septum cap closure as shown in the image below:

      Helpful?

  2. Hi, what is the difference between DMSO product# D2438 and D2650? What is Hybri-Max vs. BioPerformance certified and meets USP testing specification?

    1 answer
    1. Both D2438 and D2650 are suitable for cell culture. The D2650 is part of the Hybri-Max™ product line. Hybri-Max products have been tested for use in hybridoma creation and culture. The D2438 is part of the BioPerformance Certified group of products. These products are tested and optimized for use in biological applications. For this product and a number of others, this includes testing to meet USP and EP guidelines. Please see the links below to review a sample Certificate of Analysis for each item.
      D2650
      https://www.sigmaaldrich.com/product/sigma/d2438#product-documentation
      D2438
      https://www.sigmaaldrich.com/product/sigma/d2650#product-documentation

      Helpful?

  3. Purity grade of the product ?

    1 answer
    1. The purity of this product is listed on the lot specific Certificate of Analysis. Please navigate to the DOCUMENTATION section of the Product Detail Page to access a Certificate:
      https://www.sigmaaldrich.com/product/sigma/d2438#product-documentation

      Helpful?

  4. El DMSO es sensible a la luz, hay que tomar alguna precaución al respecto?

    1 answer
    1. This product is packaged in amber glass and is protected from light. The 10 mL size is packaged in a sealed ampule. Once opened, any content that is not used should also be stored in amber glass. For long term storage, the material may also be stored under inert gas to preserve the shelf life. Note that this material has a tendency to absorb water. Containers should be tightly sealed.

      Helpful?

  5. what are the storing conditions?

    1 answer
    1. This product is stored at room temperature. Store in a well-ventilated place. Keep cool. Please see the Material Safety Data Sheet for more information: https://www.sigmaaldrich.com/sds/sigma/d2438.

      Helpful?

  6. What is the difference between products D2438 and D8418?

    1 answer
    1. The D2438 is a BioPerformance Certified grade product suitable for cell culture, hybridoma creation, and cryopreservation. It is intended for research use only but does meet USP and EP testing requirements. The D8418 is a molecular biology-grade product suitable for DNA sequencing, PCR, and transfection. It has been tested for RNAse and DNAse. The products can be selected based on the application.

      Please view the sample Certificate of Analysis for each product to see the testing specifications associated with that item:
      https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/PDF734068.pdf
      https://www.sigmaaldrich.com/coa/SIGMA/D2438/RNBL8837

      Helpful?

  7. What is the basis for the endotoxin specification for Dimethyl sulfoxide (DMSO)?

    1 answer
    1. The industry standard for 'endotoxin free' is less than 1 EU/mL.

      Helpful?

  8. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer
    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

      Helpful?

  9. What is the molarity of DMSO?

    1 answer
    1. DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

      Helpful?

  10. Where does DMSO come from?

    1 answer
    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

1–10 of 16 Questions  

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