D6446

DOV 216,303

≥98% (HPLC)

• Synonim(y): (±)-1-(3,4-dichlorophenyl)-3-azabicyclo-[3.1.0]hexane hydrochloride
• Wzór empiryczny (zapis Hilla): C₁₁H₁₁Cl₂N · HCl
• Numer CAS: 86215-36-3
• Masa cząsteczkowa: 264.58
• NACRES: NA.77
• PubChem Substance ID: 329798827
• UNSPSC Code: 12352200
• MDL number: MFCD06407666
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: ≥10 mg/mL
• originator: Merck & Co., Inc., Kenilworth, NJ, U.S.
• storage temp.: −20°C
• SMILES string: Cl.Clc1ccc(cc1Cl)C23CNCC2C3
• InChI: 1S/C11H11Cl2N.ClH/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11;/h1-3,8,14H,4-6H2;1H
• InChI key: KAGBHVBIOJBGBD-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Serotonin-norepinephrine-dopamine reuptake inhibitor.

Triple reuptake inhibitor (TRI); serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI); IC50 values of ~20, 14, and 78 nM, respectively.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H319
• pcodes: P301 + P310 + P330 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable