D7571

Dimaprit dihydrochloride

≥98% (NMR)

• Synonim(y): Carbamimidothioic acid, 3-(dimethylamino)propyl ester, hydrochloride (1:2), Dimaprit-2HCl
• Wzór empiryczny (zapis Hilla): C₆H₁₅N₃S · 2HCl
• Numer CAS: 23256-33-9
• Masa cząsteczkowa: 234.19
• NACRES: NA.77
• PubChem Substance ID: 329798854
• UNSPSC Code: 12352200
• MDL number: MFCD00069260
• Assay: ≥98% (NMR)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (NMR)
• form: powder
• color: white to off-white
• solubility: H₂O: ≥50 mg/mL
• originator: Roche
• storage temp.: −20°C
• SMILES string: Cl.Cl.CN(C)CCCSC(N)=N
• InChI: 1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
• InChI key: DFWCPLGXFMSUCW-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

Selective histamine receptor H2 agonist.

The histamine H2 receptor influences various cardiovascular responses, including vasodilation and cardiac rhythm, regulates gastric acid secretion, and also plays a role in the immune system by inhibiting antibody production, T cell proliferation and cytokine production. Histamine receptors are members of the GPCR family, and H2 mediates cell signaling via internalization and interaction with the GTPase dynamin.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H315,H319,H335
• Ostrzeżenia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Narządy docelowe: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable