Produkty
Produkty
Wszystkie zdjęcia(2)
L5886
Lipopolysaccharides from Salmonella enterica serotype abortus equi
purified by phenol extraction
Synonim(y):
LPS
Numer MDL:
NACRES:
NA.25
Poziom jakości
200
pochodzenie biologiczne
Salmonella enterica (Serotype abortus equi)
forma
lyophilized powder
oczyszczone przez
phenol extraction
zanieczyszczenia
<3% Protein (Lowry)
transport
ambient
temp. przechowywania
2-8°C
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Opis ogólny
This product is phenol extracted from Salmonella abortus equi. The source strain is ATCC 9842. Lipopolysaccharide from Salmonella abortus equi stimulates human mononuclear cells to produce tumor necrosis factor. This LPS is also mitogenic for frog and mouse lymphocytes.
Opakowanie
10, 100 mg in glass bottle
Zastosowanie
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Działania biochem./fizjol.
Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.
Uwaga dotycząca przygotowania
The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.
Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 2 Oral
Kod klasy składowania
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Temperatura zapłonu °F
Not applicable
Temperatura zapłonu °C
Not applicable
Certyfikat analizy
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Świadectwo pochodzenia
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