SML4186

Levofloxacin hydrochloride

≥98% (HPLC), powder, DNA gyrase and topoisomerase IV inhibitor

• Wzór empiryczny (zapis Hilla): C₁₈H₂₀FN₃O₄ · xHCl
• Numer CAS: 100986-85-4
• Masa cząsteczkowa: 361.37 (free base basis)
• MDL number: MFCD00865049
• NACRES: NA.21
• UNSPSC Code: 41116107
• eCl@ss: 32120505
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: O=C1C2=CC(F)=C(C3=C2N([C@H](CO3)C)C=C1C(O)=O)N4CCN(C)CC4.[xHCl]

Opis

General description

Levofloxacin is the L-isomer of the racemic fluoroquinolone, ofloxacin. It has a more intricate fused ring structure that is linked to the oxazinoquinoline core as compared to quinolones. Levofloxacin is a broad-spectrum fluoroquinolone antibiotic that exhibits high water solubility. While the hydrochloride form of levofloxacin is freely soluble in water, levofloxacin itself is only sparingly soluble in aqueous solutions.

Application

Levofloxacin hydrochloride may be used to:

• investigate its antibacterial effects against Gram-positive and Gram-negative bacteria
• assess environmental antibiotic pollution
• study drug–food interactions in pharmacokinetic research by evaluating the impact of dietary interventions on quinolone bioavailability

Biochem/physiol Actions

Levofloxacin is a fluoroquinolone antibiotic with broad-spectrum activity, the optical S-(-) isomer of ofloxacin, which kills bacteria by blocking DNA gyrase and type IV topoisomerase—critical enzymes for DNA replication and transcription—leading to cell death. It is effective against a broad array of both Gram-positive and Gram-negative bacteria, in addition to Mycoplasmas.

Disclaimer

Hygroscopic Store with desiccant

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H302,H317,H334
• Ostrzeżenia: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
• Klasa składowania: 11 - Combustible Solids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable