U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• Synonim(y): UTP
• NACRES: NA.52
• PubChem Substance ID: 24900622
• UNSPSC Code: 41106305
• MDL number: MFCD00044310
• eCl@ss: 32119108
• Assay: ≥95 (HPLC)
• Biological source: yeast (Candida Utilis)
• Form: liquid
• Storage temp.: −20°C

Właściwości

• biological source: yeast (Candida Utilis)
• Quality Segment: 300
• assay: ≥95 (HPLC)
• form: liquid
• concentration: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• technique(s): cDNA synthesis: suitable, whole genome amplification: suitable
• color: colorless
• foreign activity: DNase and RNase, none detected
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• InChI key: MMJGIWFJVDOPJF-LLWADOMFSA-K
• Gene Information: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Opis

Application

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Biochem/physiol Actions

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

P2Y receptor agonist

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable