Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides.

Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides.

Bioorganic & medicinal chemistry letters (2009-12-08)

Abdelselam Ali, Petr Fisara, Jamie A Freemont, Stella Kyi, Adam G Meyer, Andrew G Riches, Roger M Sargent, David G Sawutz, Kathleen A Turner, Kevin N Winzenberg, Qi Yang

PMID19962303

ABSTRACT

A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.

MATERIALS

Product Number

Brand

Product Description

545953

Sigma-Aldrich

1-Aminohydantoin hydrochloride, 98%

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