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  • A short diastereoselective synthesis of orthogonally protected diaminosuccinic acid derivatives.

A short diastereoselective synthesis of orthogonally protected diaminosuccinic acid derivatives.

The Journal of organic chemistry (2004-09-18)
Kirsten Zeitler, Wolfgang Steglich
ABSTRACT

Homogeneous, Rh-catalyzed hydrogenation of heteromeric olefinic glycine dimers presents an efficient route to diastereomerically pure, orthogonally protected diaminosuccinic acid derivatives depending on the double bond geometry of the starting material. The products were obtained as racemates.