- Anti-SARS-CoV activity of nucleoside analogs having 6-chloropurine as a nucleobase.
Anti-SARS-CoV activity of nucleoside analogs having 6-chloropurine as a nucleobase.
Nucleic acids symposium series (2004) (2006-12-08)
Masahiro Ikejiri, Masayuki Saijo, Shigeru Morikawa, Shuetsu Fukushi, Tetsuya Mizutani, Ichiro Kurane, Tokumi Maruyama
PMID17150843
ABSTRACT
Nucleoside analogs that have 6-chloropurine as a nucleobase were synthesized and evaluated to develop novel anti-SARS-CoV agents. Two compounds among them showed promising activity that was comparable to mizoribine and ribavirin. Moreover, one of the compounds showed a structurally unique property.