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  • Efficient synthesis of fluoren-9-ones by the palladium-catalyzed annulation of arynes by 2-haloarenecarboxaldehydes.

Efficient synthesis of fluoren-9-ones by the palladium-catalyzed annulation of arynes by 2-haloarenecarboxaldehydes.

The Journal of organic chemistry (2008-08-08)
Jesse P Waldo, Xiaoxia Zhang, Feng Shi, Richard C Larock
ABSTRACT

Fluoren-9-ones and derivatives are readily prepared in good yields by the annulation of in situ generated arynes by 2-haloarenecarboxaldehydes in the presence of a palladium catalyst.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
9-Fluorenone, 98%
Sigma-Aldrich
2-Iodobenzaldehyde, 97%