Total synthesis of kottamide E.

Total synthesis of kottamide E.

Chemical communications (Cambridge, England) (2013-02-12)

Thomas B Parsons, Neil Spencer, Chi W Tsang, Richard S Grainger

ABSTRACT

The first synthesis of kottamide E, a marine natural product containing a 5,6-dibromoindole linked via a (Z)-enamide to an unusual 1,2-dithiolane-containing amino acid, is reported.

MATERIALS

Product Number

Brand

Product Description

92748

Sigma-Aldrich

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate, ≥97.0%

Pricing and availability is not currently available.

W259306

Sigma-Aldrich

Indole, ≥99%, FG

Pricing and availability is not currently available.

I3408

Sigma-Aldrich

Indole, ≥99%

Pricing and availability is not currently available.