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  • [Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots].

[Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (2012-07-19)
Ting Zhang, Lin Ma, Feng Wu, Ruoyun Chen
ABSTRACT

To study chemical constituents from the roots of Saussurea lappa. Chemical constituents were separated and purified by various techniques such as silica gel column chromatography, Sephadex LH-20 and reversed phase RP-18 column chromatography. Their structures were identified on the basis of spectral data. Seventeen compounds were separated and identified as ascleposide E(1), (+)-1-hydroxypinoresinol-4"-O-methyl ester-4'-beta-D-glucopyranoside (2), (+)-1 -hydroxypinoresinol-4"-O-beta-D-glucopyranoside(3), (+)-1-hydroxypinoresinol-1-O-P-D-glucopyranoside (4), phenyl-beta-D-glucopyranoside (5), benzyl-beta-D-glucopyranoside (6), n-butyl-beta-D-glucopyranoside (7), ilicic alcohol (8), beta-cyclocostunolide (9), reynosin (10), 11beta, 13-dihydroreynosin (11), arbusculin A(12), 1beta-hydroxy-arbusculin A (13), santamarin (14), dehydrocostuslactone (15), 11beta, 13-dihydro-3-epizaluzanin C(16)and costunolide (17). Compounds 1-2 were separated from this genus for the first time,and compounds 3,5-7 were separated from this plant for the first time.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Costunolide, ≥97% (HPLC)