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Merck

55453

β-羟基异戊酸

≥95.0% (T)

β-Hydroxyisovaleric acid

别名:

3-羟基-3-甲基丁酸

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1 G

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经验公式(希尔记法):
C5H10O3
化学文摘社编号:
分子量:
118.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1743952

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产品名称

β-羟基异戊酸, ≥95.0% (T)

InChI

1S/C5H10O3/c1-5(2,8)3-4(6)7/h8H,3H2,1-2H3,(H,6,7)

SMILES string

CC(C)(O)CC(O)=O

InChI key

AXFYFNCPONWUHW-UHFFFAOYSA-N

assay

≥95.0% (T)

refractive index

n20/D 1.4415 (lit.)

bp

88 °C/1 mmHg (lit.)

mp

−80 °C (lit.)

density

0.938 g/mL at 25 °C (lit.)

functional group

carboxylic acid
hydroxyl

Quality Level

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此商品
554524515057400
assay

≥95.0% (T)

assay

≥98.0% (T)

assay

≥97.0% (T)

assay

≥99.0% (T)

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

200

density

0.938 g/mL at 25 °C (lit.)

density

-

density

-

density

-

mp

−80 °C (lit.)

mp

64-67 °C

mp

≥300 °C (dec.)

mp

~133 °C

refractive index

n20/D 1.4415 (lit.)

refractive index

-

refractive index

-

refractive index

-

bp

88 °C/1 mmHg (lit.)

bp

-

bp

-

bp

-

Application

β-羟基异戊酸可作为甾体醇的前体。
它被广泛用于合成炭疽四糖及其类似物,作为炭疽疫苗的候选物。[1][2]β-羟基异戊酸也可用于合成 β-内酯通过 2-甲基-6-硝基苯酐 (MNBA) 分子内脱水缩合反应生成。[3]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R Santer et al.
Molecular genetics and metabolism, 79(3), 160-166 (2003-07-12)
We report the clinical course and biochemical findings of a 10-year-old, mentally retarded girl with late-onset holocarboxylase synthetase (HCS, gene symbol HLCS) deficiency and only partial response to biotin. On treatment, even with an unusually high dose of 200mg/day, activities
Carlos Hermano da Justa Pinheiro et al.
European journal of applied physiology, 112(7), 2531-2537 (2011-11-15)
Beta-hydroxy-beta-methylbutyrate (HMB) is a metabolite derived from leucine. The anti-catabolic effect of HMB is well documented but its effect upon skeletal muscle strength and fatigue is still uncertain. In the present study, male Wistar rats were supplemented with HMB (320
Shawn Portal et al.
European journal of applied physiology, 111(9), 2261-2269 (2011-02-18)
The use of ergogenic nutritional supplements is becoming inseparable from competitive sports. β-Hydroxy-β-Methylbutyric acid (HMB) has recently been suggested to promote fat-free mass (FFM) and strength gains during resistance training in adults. In this prospective randomized, double-blind, placebo-controlled study, we
C Flummer et al.
Journal of animal science, 90 Suppl 4, 372-374 (2013-02-13)
This trial was conducted to investigate whether β-hydroxy β-methyl butyrate (HMB) supplementation during late gestation and throughout lactation would influence colostrum and milk production of sows and neonatal piglet survival (0 to 24 h). Control sows (CON; n = 8)
De novo asymmetric synthesis of anthrax tetrasaccharide and related tetrasaccharide.
Guo, Haibing and O?Doherty, George A
The Journal of Organic Chemistry, 73(14), 5211-5220 (2008)

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