N-terminal GST-tagged, recombinant human EGF Receptor, amino acids 696-end containing the mutation L861Q
Product Source: baculovirus in Sf21 insect cells
應用
Research Category Inflammation & Immunology
生化/生理作用
Protein Target: EGFR
Target Sub-Family: TK
外觀
Glutathione-agarose
準備報告
6 months at -70°C
分析報告
routinely evaluated by phosphorylation of 0.1mg/ml Poly (Glu4-Tyr)
其他說明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
The New England journal of medicine, 350(21), 2129-2139 (2004-05-01)
Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which targets the epidermal growth factor receptor (EGFR). However, about 10 percent of patients have a rapid and often dramatic clinical response. The molecular mechanisms