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Merck

341088

1,9-二甲基亚甲蓝 氯化锌复盐

Dye content 80 %

1,9-Dimethyl-Methylene Blue zinc chloride double salt

别名:

DMMB, 泰勒蓝

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1 G

$212.00

$212.00


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关于此项目

经验公式(希尔记法):
C18H22ClN3S · 0.5ZnCl2
化学文摘社编号:
分子量:
416.05
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:

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产品名称

1,9-二甲基亚甲蓝 氯化锌复盐, Dye content 80 %

InChI

1S/2C18H22N3S.4ClH.Zn/c2*1-11-7-13(20(3)4)9-15-17(11)19-18-12(2)8-14(21(5)6)10-16(18)22-15;;;;;/h2*7-10H,1-6H3;4*1H;/q2*+1;;;;;+2/p-4

SMILES string

[Cl-].[Cl-].Cl[Zn]Cl.CN(C)c1cc(C)c2N=C3C(C)=C\C(C=C3Sc2c1)=[N+](/C)C.CN(C)c4cc(C)c5N=C6C(C)=C\C(C=C6Sc5c4)=[N+](/C)C

InChI key

MKLBAKXCEQNMBC-UHFFFAOYSA-J

form

powder

composition

Dye content, 80%

technique(s)

titration: suitable

impurities

<20% water

mp

250 °C (dec.) (lit.)

λmax

649 nm

ε (extinction coefficient)

≥10000 at 243-249 nm in H2O
≥18000 at 285-291 nm in H2O
≥25000 at 594-600 nm in H2O
≥35000 at 646-652 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

Application

1,9-二甲基-亚甲蓝氯化锌复盐已用于硫酸化糖胺聚糖的定量。[1]
DMMB是一种阳离子染料,能特异性结合硫酸化糖胺聚糖(sGAG),吸光度约为525 nm。
DMMB是一种阳离子染料,能特异性结合硫酸化糖胺聚糖(sGAG),吸光度约为525 nm。它已被用于定量蛋白多糖中的氨基葡萄糖,如硫酸软骨素、硫酸角蛋白、硫酸乙酰肝素和sGAG链。这种方法的一个限制是sGAG-DMMB络合物在溶液中不稳定,可能会沉淀。复合物的沉淀显示提高了稳定性。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

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Hyeon-Son Choi et al.
Biological & pharmaceutical bulletin, 39(12), 2042-2051 (2016-12-03)
The anti-osteoarthritic activity of the methanol fraction of deer bone oil extract (DBO-M) was evaluated in interleukin (IL)-1β-inflamed primary rabbit chondrocytes and in rats with monosodium iodoacetate (MIA)-induced osteoarthritis. The active compound in DBO-M was analyzed using a direct infusion
A Herrero-Mendez et al.
Journal of tissue engineering and regenerative medicine, 10(12), 1000-1011 (2014-03-07)
Biomaterials and, especially, scaffolds may function as temporary extracellular matrix (ECM), mimicking in vivo environmental structures and facilitating cell growth and tissue regeneration. ECM is composed mostly of glycosaminoglycans (GAGs) and proteins, the ratio of GAGs, hyaluronic acid (HA):sulphated GAGs
High-throughput bone and cartilage micropellet manufacture, followed by assembly of micropellets into biphasic osteochondral tissue.
Babur BK
Cell and Tissue Research, 361(3), 755-768 (2015)
Tianyi Wang et al.
Tissue engineering. Part A, 22(23-24), 1348-1356 (2016-10-21)
Cell-based therapies offer great promise for repairing cartilage. Previous strategies often involved using a single cell population such as stem cells or chondrocytes. A mixed cell population may offer an alternative strategy for cartilage regeneration while overcoming donor scarcity. We
Makwese Maepa et al.
Tissue engineering. Part A, 25(15-16), 1137-1145 (2018-12-05)
Eucomis autumnalis is one plant that is used by various traditional healers to alleviate the signs and symptoms associated with osteoarthritis. Although the exact mechanisms remain unknown, we hypothesized that this plant can induce chondrogenesis. In this work, we explored

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