09926
N-己酰基- DL -高丝氨酸内酯
≥97.0% (HPLC)
别名:
N-己酰基- DL -高丝氨酸内酯
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关于此项目
经验公式（希尔记法）:
C10H17NO3
化学文摘社编号:
分子量:
199.25
Beilstein:
1640340
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26
跳至
化驗
≥97.0% (HPLC)
形狀
powder or crystals
技術
LC/MS: suitable
顏色
white to faint beige
mp
101-106 °C
儲存溫度
2-8°C
SMILES 字串
CCCCCC(=O)NC1CCOC1=O
CCCCCC(=O)NC1CCOC1=O
InChI
1S/C10H17NO3/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)
InChI 密鑰
ZJFKKPDLNLCPNP-UHFFFAOYSA-N
1 of 4
此商品 | 56395 | 10937 | 10940 |
|---|---|---|---|
| form powder or crystals | form powder or crystals | form powder | form powder with small lumps |
| assay ≥97.0% (HPLC) | assay ≥96% (HPLC) | assay ≥97.0% (HPLC) | assay ≥97.0% (HPLC) |
| technique(s) LC/MS: suitable | technique(s) - | technique(s) - | technique(s) - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| mp 101-106 °C | mp - | mp - | mp - |
| color white to faint beige | color white to off-white | color white to slightly yellow | color white to faintly beige |
應用
在一个紫色色杆菌突变体中诱导紫花地丁的表达，该突变体通常不能产生高丝氨酸内酯。[1]
生化／生理作用
N-己酰基-DL-高丝氨酸内酯是 N-酰基-高丝氨酸内酯家族的一员。N-酰基高丝氨酸内酯 (AHL) 调节革兰阴性细菌 、埃希杆菌 和沙门氏菌的基因表达，参与群体感应、细菌间的细胞间通讯。一些 AHL 是人类免疫细胞（如中性粒细胞）的强效化学引诱物。
群体感应信号生成
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Albert Soler et al.
International journal of environmental research and public health, 15(5) (2018-05-23)
Quorum sensing (QS) is a mechanism dependent on bacterial density. This coordinated process is mediated by the synthesis and the secretion of signal molecules, called autoinducers (AIs). N-acyl-homoserine lactones (AHLs) are the most common AIs that are used by Gram-negative
Daniel Wynn et al.
The Analyst, 143(19), 4774-4782 (2018-09-15)
There are an estimated 48 million cases of foodborne illness in the United States every year. In general, these illnesses are the result of unintentional contamination and improper food handling. Because bacterial contamination plays a major role in food spoilage
Thommie Karlsson et al.
Journal of leukocyte biology, 91(1), 15-26 (2011-08-03)
In gram-negative bacteria, cell-cell communication based on HSL QS molecules is known to coordinate the production of virulence factors and biofilms. These bacterial signals can also modulate human immune cell behavior. Using a Transwell migration assay, we found that human
Tomohiro Morohoshi et al.
FEMS microbiology letters, 279(1), 124-130 (2008-01-08)
In tests, Chromobacterium violaceum ATCC 12472 produced several N-acyl-L-homoserine lactones (AHLs). Of these, N-(3-hydroxydecanoyl)-L-homoserine lactone was dominant, and controlled violacein production by quorum sensing. Strain VIR07, an AHL-deficient mutant, did not produce violacein. Violacein production in VIR07 was induced by
L Eberl
Systematic and applied microbiology, 22(4), 493-506 (2000-05-04)
The view of bacteria as unicellular organisms has strong roots in the tradition of culturing bacteria in liquid media. However, in nature microbial activity is mainly associated with surfaces where bacteria form highly structured and cooperative consortia which are commonly
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