ESR2
estrogen receptor 2 (ER beta)
Synonyms:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Species:
Human ESR2 (2100), Mouse Esr2 (13983), Rat Esr2 (25149), dog ESR2 (403639), chicken ESR2 (395575), domestic guinea pig Esr2 (100731304), Domestic Rabbit ESR2 (100346748), domestic cat ESR2 (101086317), Horse ESR2 (100033964), cow ESR2 (281146) ...More
UniProtKB ID:
Gene ID:
- Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(13983) estrogen receptor 2 (beta)
- Rat(25149) estrogen receptor 2 (ER beta)
- dog(403639) estrogen receptor 2 (ER beta)
- chicken(395575) estrogen receptor 2 (ER beta)
- domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
- Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
- domestic cat(101086317) estrogen receptor 2 (ER beta)
- Horse(100033964) estrogen receptor 2 (ER beta)
- cow(281146) estrogen receptor 2 (ER beta)
- Goat(100860823) estrogen receptor 2 (ER beta)
- sheep(443066) estrogen receptor 2 (ER beta)
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Small Molecule - Activator
Product Number
Description
Species
β-Nicotinamide adenine dinucleotide hydrate, suitable for cell culture, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Species
human
β-Nicotinamide adenine dinucleotide hydrate, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Species
human
Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Fulvestrant for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Estrogen Receptor β Antibody, clone 9.88, clone 9.88, from mouse,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-ESR2 antibody produced in mouse, clone 3F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-ESR2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Estrogen Receptor-β antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-ESR2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rat
Application
western blot
Cell Lines
Product Number
Description
Species
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
esiRNA
Product Number
Description
Species