• Home
  • Search Results
  • Nickel-catalyzed carboannulation reaction of o-bromobenzyl zinc bromide with unsaturated compounds.

Nickel-catalyzed carboannulation reaction of o-bromobenzyl zinc bromide with unsaturated compounds.

Organic letters (2007-11-10)
Ruixue Deng, Liangdong Sun, Zhi Li
ABSTRACT

A number of indenes have been prepared in good yields by treating o-bromobenzyl zinc bromide 1 with various terminal and internal alkynes in the presence of a nickel catalyst. The nickel-catalyzed carboannulation reaction was successfully extended to the synthesis of indane derivatives by reaction of 1 with acrylates and styrene.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Zinc bromide, 99.999% trace metals basis
Sigma-Aldrich
Zinc bromide, AnhydroBeads, −10 mesh, 99.999% trace metals basis