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Dioctyl sulfosuccinate analysis in near-shore Gulf of Mexico water by direct-injection liquid chromatography-tandem mass spectrometry.

Journal of chromatography. A (2012-03-01)
Johnson Mathew, David L Schroeder, Lawrence B Zintek, Caitlin R Schupp, Michael G Kosempa, Adam M Zachary, George C Schupp, Dennis J Wesolowski
ABSTRACT

Dioctyl sulfosuccinate (DOSS) was a major component of the dispersants most used in the 2010 Deepwater Horizon Oil Spill incident response. This analytical method quantifies salt water DOSS concentrations to a reporting limit of 20 μg/L, which was below the United States Environmental Protection Agency's (U.S. EPA) 40 μg/L DOSS Aquatic Life Benchmark. DOSS in Gulf of Mexico water samples were analyzed by direct-injection reversed-phase liquid chromatography-tandem mass spectrometry (LC-MS/MS). Sample preparation with 50% acetonitrile (ACN) enabled quantitative transfer of DOSS and increased DOSS response 20-fold by reducing aggregation. This increased sensitivity enabled the detection of a confirmatory transition over the calibration range of 10-200 μg/L. U.S. EPA Region 5 and Region 6 laboratories analyzed hundreds of near-shore surface Gulf of Mexico water samples, none contained more than the 20 ppb reporting limit. The matrix spike DOSS/deuterated surrogate (DOSS-D34) correlation of determination varied with mobile phase modifier (ammonium formate R(2)=0.95 and formic acid R(2)=0.27). Using ammonium formate, DOSS-D34 accurately measured DOSS matrix effect. The near-shore sodium concentrations varied more than 10,000-fold, but were not strongly correlated with DOSS recovery. DOSS detection by LC-MS/MS enabled rapid analysis which was valuable in guiding incident response.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Dioctyl sulfosuccinate sodium salt, ≥97%
Sigma-Aldrich
Docusate sodium salt, BioXtra, ≥99%
Sigma-Aldrich
Docusate sodium salt, purum, ≥96.0% (TLC)
Sigma-Aldrich
Docusate sodium salt, BioUltra, ≥99.0% (TLC)
Sigma-Aldrich
Docusate sodium, meets USP testing specifications