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[Intestinal dipeptidases and their regulation in chicks of different ages].

Zhurnal evoliutsionnoi biokhimii i fiziologii (1983-11-01)
I L Tarvid, R I Kushak
ABSTRACT

Studies have been made of changes in catalytic activity and regulatory properties of membrane and intracellular glycyl-valine dipeptidase from the small intestine of chicks ageing from 1 to 40 days. Gradual decrease in the activity of membrane glycyl-valine dipeptidase was found during postnatal life together with formation of proximodistal gradient in the distribution along the intestine with maximal activity in the distal part. The magnitude and direction of regulatory effects of modificators (tributyrine, sucrose, L-methionine) depend on the age of chicks. Intracellular enzyme does not undergo any significant changes in its regulatory properties and in the level of its activity along the intestine during postnatal development of chicks.