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Food protective effects of Periploca sepium oil and its active component against stored food mites.

Journal of food protection (2012-01-10)
Eun-Young Jeong, Kyoung-Shik Cho, Hoi-Seon Lee

The aim of this study was to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae. Based on its 50% lethal dose (LD(50) ) value, P. sepium oil (8.45 μg/cm(2)) was highly active against T. putrescentiae. The active constituent of P. sepium was isolated by chromatographic techniques and identified as 2-hydroxy-4-methoxybenzaldehyde. In the comparison with synthetic acaricides, the acaricidal activity of 2-hydroxy-4-methoxybenzaldehyde (0.94 μg/cm(2)) against T. putrescentiae was 12.2- and 31.2-fold greater than those of benzyl benzoate (11.45 μg/cm(2)) and N,N-diethyl-m-toluamide (29.33 μg/cm(2)), respectively. To establish structure-activity relationships, the acaricidal activities of 2-hydroxy-4-methoxybenzaldehyde and its derivatives against T. putrescentiae were determined by using an impregnated fabric disk bioassay. On the basis of LD(50) values, 4-methoxybenzaldehyde (0.48 μg/cm(2)) was the most effective against T. putrescentiae, followed by 3-methoxybenzaldehyde (0.82 μg/cm(2)), 2-hydroxy-5-methoxybenzaldehyde (0.92 μg/cm(2)), 2-methoxybenzaldehyde (0.95 μg/cm(2)), 2-hydroxybenzaldehyde (0.97 μg/cm(2)), and 2-hydroxy-3-methoxybenzaldehyde (2.35 μg/cm(2)). These results indicate that the introduction of a hydroxyl and/or methoxy group into the benzaldehyde skeleton increased the acaricidal activity. Therefore, 2-hydroxy-4-methoxybenzaldehyde and its derivatives could potentially be used as potent mite control agents.

Product Number
Product Description

2-Methoxybenzaldehyde, 98%
2-Hydroxy-5-methoxybenzaldehyde, 98%

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