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Merck

HLA-DRA

major histocompatibility complex, class II, DR alpha

Synonymes:
HLA-DRA1, MLRW
Espèce(s):
Human HLA-DRA (3122)
ID UniProtKB:
P01903, A2BET4, Q30160, Q6IAZ1, Q861I2, Q9TP70
ID du gène:
  • Human(3122) Summary: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
HPA053176
Anti-HLA-DRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
SAB4700731
Monoclonal Anti-HLA-DR antibody produced in mouse, clone L243, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
dog, human, nonhuman primates
Application
FUNC
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4700659
Monoclonal Anti-HLA-DR-FITC antibody produced in mouse, clone MEM-12, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
SAB4700653
Monoclonal Anti-HLA-DR antibody produced in mouse, clone MEM-12, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
MAB4201F
Anti-HLA-DR Antibody, clone 169-1B5.1, FITC conjugated, clone 169-1B5.1, Chemicon®, from mouse,
Espèces réactives
human
Application
flow cytometry

esiRNA

Numéro du produit
Description
Espèce(s)
EHU226621
MISSION® esiRNA, targeting human HLA-DRA (2),
Espèce(s)
human
EHU218921
MISSION® esiRNA, targeting human HLA-DRA (1),
Espèce(s)
human