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M7769

IgG2a, Kappa from murine myeloma

clone UPC 10, ascites fluid, lyophilized powder

Synonym(s):

Mouse IgG2a-κ

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5 mg

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$442.00
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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00164800
Conjugate:
unconjugated
Clone:
UPC 10, monoclonal
Application:
—
Citations:
20

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biological source

mouse

Quality Segment

300

conjugate

unconjugated

antibody form

ascites fluid

clone

UPC 10, monoclonal

form

lyophilized powder

storage temp.

2-8°C

target post-translational modification

unmodified

General description

The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. The hapten binding specificity of the UPC-10 line is for β-2-6-linked fructosan. The ascites produced from the UPC-10 tumor line contains IgG2a, K in addition to normal levels of other mouse immunoglobulins and serum proteins. The ascites fluid is clarified by centrifugation and filtration. IgG2a (immunoglobulin G 2a) is one of the subclasses of rat immunoglobulins, which also include IgG1, IgG2b and IgG2c.PMID 4137315

Immunogen

The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice.

Application

IgG2a, Kappa from murine myeloma has been used in immunofluorescencePMID 10706733 and immunohistochemistry.PMID 9346929

Biochem/physiol Actions

The IgG2a (immunoglobulin G 2a) plays a vital role in stimulating autoimmunity in mice. This gene is expressed at high level during virus infection. IgG2a offers host defence through activation of complement system. This antibody has specificity towards Fc receptors expressed on phagocytes and stimulates antibody-dependent cell mediated cytotoxicity. IgG2a also induces macrophage-mediated opsonophagocytosis, which has been observed in response to influenza virus and leads to its clearance from the infected cells.
Antigen Specificity: β-2,6-fructosan

Trace amounts of lambda chain may be present.

Physical form

The product provided is lyophilized from 0.01 M phosphate buffered saline, pH 7.2, with no preservatives added.

Preparation Note

Storage and Stability: Store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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description

clone UPC 10, ascites fluid, lyophilized powder

description

clone MOPC 195, ascites fluid, lyophilized powder

description

clone TEPC 15, purified immunoglobulin, buffered aqueous solution

description

clone MOPC 21, ascites fluid, lyophilized powder

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

clone

UPC 10, monoclonal

clone

MOPC 195, monoclonal

clone

TEPC 15, monoclonal

clone

MOPC 21, monoclonal

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

ascites fluid

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

form

lyophilized powder

form

lyophilized powder

form

buffered aqueous solution

form

lyophilized powder

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

200

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Storage Class

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flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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