PHR1640

Citalopram-Hydrobromid

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Citalopram -hydrobromid, 1-[3-(Dimethylamino)-propyl]-1-(4-fluorphenyl)-1,3-dihydro-5-isobenzofurancarbonitril -hydrobromid
• Empirische Formel (Hill-System): C₂₀H₂₁FN₂O · HBr
• CAS-Nummer: 59729-32-7
• Molekulargewicht: 405.30
• EG-Nummer: 261-890-6
• MDL-Nummer: MFCD02101306
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823528
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. Y0001008; traceable to USP 1134233
• API-Familie: citalopram
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: Br[H].CN(C)CCCC1(OCc2cc(ccc12)C#N)c3ccc(F)cc3
• InChI: 1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H
• InChIKey: WIHMBLDNRMIGDW-UHFFFAOYSA-N
• Angaben zum Gen: human ... SLC6A4(6532)

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Citalopram Hydrobromide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations[1][2][3] by spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Wirksamer und selektiver Serotonin-Aufnahme-Hemmer (K_i = 5.4 nM); Antidepressivum

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Sonstige Hinweise

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7789 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302,H336,H361d,H412
• P-Sätze: P202 - P261 - P264 - P273 - P301 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable